Leipzig University
Closing soon
2 weeks ago
PhD Position in PTEN-Dependent Craniofacial and Skeletal Biology Leipzig University in Germany
Degree Level
PhD
Field of study
Metabolism
Funding
Available
Deadline
Oct 31, 2026
Country
Germany
University
Leipzig University

How do I apply for this?
Sign in for free to reveal details, requirements, and source links.
More information can be found here
Keywords
Suggested positions
About this position
Leipzig University Medical Center (UKL), within the Medical Faculty and the Department of Orthodontics, offers a fully funded PhD position in PTEN-dependent craniofacial and skeletal biology. The project is part of a DFG-funded collaborative research effort and is embedded in the research group Cranio- and Orofacial Development.
The PhD project focuses on how loss of PTEN in the osteoblast lineage affects postnatal craniofacial tissue homeostasis. Research will concentrate on teeth and periodontal tissues, alveolar and craniofacial bone, and the temporomandibular joint (TMJ). The work aims to reveal how PTEN-dependent signaling influences tissue architecture, bone remodeling, cellular states, and molecular programs after postnatal PTEN deletion.
A complementary part of the project addresses the associated adipose/metabolic phenotype in collaboration with Dr. Antje Garten and her group in Molecular Endocrinology at the Center for Pediatric Research. This makes the position especially attractive for candidates interested in linking local craniofacial phenotypes with systemic metabolic alterations.
The project combines experimental and computational approaches, including inducible transgenic mouse models, genetic reporter systems, histology, immunofluorescence, advanced microscopy, micro-computed tomography, spatial transcriptomics, molecular biology, quantitative image analysis, proteomic integration, and bioinformatic analyses.
The university is seeking a highly motivated candidate with a Master of Science degree or diploma in Biology, Molecular Biology, Biochemistry, Biotechnology, Bioinformatics, or Chemistry. Applicants should have a strong interest in craniofacial biology, mechanobiology, or regenerative medicine, plus experience in molecular biology, cell biology, animal models, and/or bioinformatics. Good communication skills and excellent English are required. The working environment is international and interdisciplinary.
The position is fully funded for 3 years and offers access to cutting-edge technologies, international collaboration, advanced imaging, and opportunities for conference participation and exchange. The application deadline is 31 October 2026.
To apply, submit a single PDF containing a cover letter describing your research experience and motivation, a CV, copies of relevant qualifications (and animal-course certificates if applicable), and contact details for two referees. Applications should be emailed to [email protected].
Funding details
Available
What's required
Applicants should hold a Master of Science degree or diploma in Biology, Molecular Biology, Biochemistry, Biotechnology, Bioinformatics, or Chemistry. The post seeks candidates with interest in craniofacial biology, mechanobiology, or regenerative medicine, and experience in molecular biology, cell biology, animal models, and/or bioinformatics. Good communication skills and excellent proficiency in English are required.
How to apply
Send a single PDF by email to [email protected]. Include a cover letter, CV, copies of relevant qualifications (and animal-course certificates if applicable), and contact details of two referees.
Ask ApplyKite AI

How do I apply for this?
Sign in for free to reveal details, requirements, and source links.