University Hospital Münster
5 days ago
PhD Student in Biophysics and Cryo-ET at University Hospital Münster University Hospital Münster in Germany
Degree Level
PhD
Field of study
Cell Biology
Funding
Fixed-term PhD position for 3 years, part-time at 65%, paid according to TV-L E13 with extra annual payment and company pension plan (VBL).
Country
Germany
University
University Hospital Münster

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About this position
University Hospital Münster is advertising a PhD Student position in Biophysics within the Institute of Molecular Physics and Biophysics and the Center for Soft Nanoscience. The project is embedded in the DFG-funded Collaborative Research Centre 1748, Principles of Reproduction, and is based in the research group of Prof. Dr. Christos Gatsogiannis.
The research focuses on the in situ structural analysis of ion channels in the flagellum of human sperm using advanced cryo-EM methods. The advertised work includes developing and optimizing workflows for cryo-correlative light and electron microscopy (cryo-CLEM), preparing cryo-lamellae for cryo-electron tomography (cryo-ET) with cryo-FIB milling, processing cryo-ET data, subtomogram averaging, image processing, tomogram segmentation, molecular modelling, and structural analysis. Tools mentioned include PyMOL, ChimeraX, and AlphaFold.
The position is part of the Integrated Research Training Group Reproduction.MS PhD-Training Centre in Translational Science and offers a 3-year fixed-term appointment at 65% part-time with salary according to TV-L E13, plus annual bonus payment and a company pension plan (VBL). Additional benefits include vacation, training opportunities, a supportive team environment, health and work-life balance support, sports programs, job ticket, jobrad, company events, cafeteria, and emergency childcare.
Applicants should hold a Master’s degree in biophysics, cell biology, structural biology, or a related field. The post asks for strong interest in structural biology and cryo-ET methods, independent and responsible working style, strong communication and organizational skills, and excellent spoken and written English. German is advantageous. Experience in cryo-EM, structural biology, cell biology, or biophysics is helpful but not mandatory; motivated candidates with strong biological or structural training are encouraged to apply.
To apply, use the online career portal and submit a motivation letter, a summary of your Master’s thesis, transcripts and degree certificates, and two recommendation letters or reference contacts. For questions, contact Prof. Dr. Christos Gatsogiannis at [email protected].
Funding details
Fixed-term PhD position for 3 years, part-time at 65%, paid according to TV-L E13 with extra annual payment and company pension plan (VBL).
What's required
Master’s degree in biophysics, cell biology, structural biology, or a related field. Strong interest in structural biology and in developing and applying cryo-ET methods. Ability to work independently, systematically, and responsibly, with strong communication and organizational skills. Excellent spoken and written English; German language skills are advantageous. Experience in cryo-EM, structural biology, cell biology, or biophysics is advantageous, but candidates with strong biological or structural training and motivation to learn in situ structural workflows are welcome.
How to apply
Apply via the career portal using the provided application link. Include a motivation letter, a summary of your Master’s thesis, transcript and degree certificates, and two recommendation letters or reference contacts.
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