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University of Zurich

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PhD Student Position in Enzymology and Enzyme Engineering University of Zurich in Switzerland

Degree Level

PhD

Field of study

Biochemistry

Funding

Full funding available
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Country

Switzerland

University

University of Zurich

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Keywords

Biochemistry
Chemistry
Biology
High-throughput Screening
Chemical Synthesis
Protein Engineering
Enzyme Engineering

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About this position

PhD Student Position in Enzymology and Enzyme Engineering at the University of Zurich, Department of Chemistry, in the group of Prof. Dr. Alexandria (Ali) Deliz Liang. The lab focuses on fundamental enzymology and methods in enzyme engineering, including genetic code expansion.

The project is interdisciplinary and includes cloning, expression, purification, and activity characterization of target enzymes; chemical synthesis of substrates and assay probes; assay development for screening enzymatic activity; creation and high-throughput screening of DNA libraries; NGS and computational analysis of variants; Python scripting for data analysis; and mechanistic studies to understand how mutations affect catalysis.

Applicants should hold an MS degree in chemistry, biochemistry, or a related field. Required experience includes cloning, protein expression and purification, and chemical synthesis. Strong experimental design skills, scientific integrity, proactive planning, ability to integrate feedback, and excellent English communication skills are essential. Willingness to learn Python and work in a highly interdisciplinary environment is also required. Experience in enzyme assay development, protein engineering, and light scripting for data analysis is highly desirable.

This is a PhD employment position at the standard 80% rate for PhD students in the Department of Chemistry. No specific stipend amount is stated. The position is based in Zürich, Switzerland.

Apply via the university portal using the Apply now button. Submit a single PDF with a 1-page cover letter, CV, and the names of two referees. Applications are reviewed on a rolling basis, so early submission is encouraged.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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