Publisher
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Utrecht University

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Postdoc Position in Medicinal Chemistry for Piezo1 Inhibitor Discovery Utrecht University in Netherlands

Degree Level

Postdoc

Field of study

Computer Science

Funding

Paid postdoc position for one year with possible one-year extension after positive evaluation. Gross monthly salary is €3,706 to €5,760 based on qualifications and experience (salary scale 10, 38-hour week), plus 8% holiday pay, 8.3% year-end bonus, pension scheme, partially paid parental leave, flexible employment terms, and additional benefits.

Deadline

Nov 19, 2026

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Country

Netherlands

University

Utrecht University

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Keywords

Computer Science
Chemistry
Biology
Chemical Synthesis
Chemical Biology
Medical Science
Sickle Cell Disease
Pharmacy
Pharmaceutical Chemistry
Virtual Screening

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About this position

Utrecht University is advertising a postdoc position in medicinal chemistry within the Chemical Biology and Drug Discovery division of the Utrecht Institute for Pharmaceutical Sciences (UIPS), in collaboration with researchers at UMC Utrecht. The project focuses on the discovery and optimization of novel Piezo1 inhibitors for sickle cell disease, combining virtual screening, AI techniques, computational drug discovery, organic synthesis, and chemical biology.

The successful candidate will join the research group of prof. dr. Roland Pieters and work in a multidisciplinary environment with access to modern synthetic labs, analytical instrumentation, biolabs, and high-performance computing facilities. The role includes close interaction with the partner group at UMC Utrecht, where compounds will be assayed, and participation in periodic user committee meetings.

Eligibility highlights: completed PhD in medicinal chemistry; experience in organic synthesis of drug-like compounds; experience in molecular modelling/docking and development of bioactive compounds; strong written and spoken English.

Funding and conditions: this is a paid postdoc appointment for one year, with the possibility of a one-year extension after positive evaluation. Salary is €3,706–€5,760 gross per month (scale 10, 38 hours/week), plus 8% holiday pay, 8.3% year-end bonus, pension, partially paid parental leave, flexible employment terms, and additional benefits.

Deadline: 19 November 2026.

How to apply: submit your application through the AcademicTransfer vacancy page. For scientific questions, contact Roland J. Pieters at [email protected]. For questions about the application procedure, contact [email protected].

Funding details

Paid postdoc position for one year with possible one-year extension after positive evaluation. Gross monthly salary is €3,706 to €5,760 based on qualifications and experience (salary scale 10, 38-hour week), plus 8% holiday pay, 8.3% year-end bonus, pension scheme, partially paid parental leave, flexible employment terms, and additional benefits.

What's required

Completed PhD in Medicinal Chemistry; experience in organic synthesis of drug-like compounds; experience in molecular modelling/docking and in the creation and development of bioactive compounds; proficiency in written and spoken English.

How to apply

Apply via the AcademicTransfer vacancy page. For questions about the position, email prof dr. Roland J. Pieters at [email protected]. For application procedure questions, email [email protected].

More information can be found here

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