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Duke University

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Postdoctoral Associate in Focused Antibiotic Drug Design at Duke University Duke University in United States

Degree Level

Postdoc

Field of study

Computer Science

Funding

The position is funded through funded programs and is an initial one-year appointment with the possibility of renewal by mutual agreement and subject to continued funding from a milestone-oriented sponsor.

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Country

United States

University

Duke University

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Keywords

Computer Science
Chemistry
Microbiology
Biology
Chemical Synthesis
Chemical Biology
Medical Science
Pharmacy
Computer-aided Drug Design

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About this position

Postdoctoral Associate position at Duke University in the Franz Laboratory (Department of Chemistry) focused on focused antibiotic drug design, synthetic chemistry, chemical biology, microbiology, and computational drug design.

The project aims to create pathogen-selective, enzyme-activated antibiotic prodrugs that treat bacterial infections while sparing the gut microbiome. The successful candidate will join an integrated experimental and computational team and contribute to iterative design-synthesize-test workflows.

Responsibilities include synthesizing, characterizing, and evaluating candidate compounds in microbiological assays; collecting and analyzing data; maintaining research records; preparing reports, manuscripts, abstracts, and presentations; attending group meetings; and mentoring graduate and undergraduate researchers.

Required: a Ph.D. in Chemistry by the start date, with expertise in synthetic chemistry. Preferred experience includes chemical biology, microbiology, cell biology, pathogen disease research, computational approaches to drug design, bioassay development, or bioanalytical methods. Strong communication skills, independent productivity, and collaborative teamwork are emphasized.

Start date is October 2026 (flexible). The initial appointment is for one year, renewable by mutual agreement and subject to continued funding. Apply by uploading a CV, cover letter describing research background/interests/goals, and contact information for three references via AcademicJobsOnline. Applications are accepted until the position is filled.

Funding details

The position is funded through funded programs and is an initial one-year appointment with the possibility of renewal by mutual agreement and subject to continued funding from a milestone-oriented sponsor.

What's required

Applicants should have a Ph.D. in Chemistry by the start date, with specific expertise in synthetic chemistry. Strong candidates should also have experience in at least one of chemical biology, microbiology, cell biology, pathogen disease research, computational approaches to drug design, bioassay development, or bioanalytical methods. Strong communication skills, independent research productivity, and the ability to work both independently and collaboratively in an interdisciplinary team are expected.

How to apply

Apply through AcademicJobsOnline by uploading a CV, cover letter, and contact information for three references. Applications are reviewed until the position is filled.

More information can be found here

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