University of Minnesota
1 week ago
Postdoctoral Associate in Colorectal Cancer Malignant Transformation and Tumor Immunology University of Minnesota in United States
Degree Level
Postdoc
Field of study
Cell Biology
Funding
NIH-funded postdoctoral positions supported by a recently funded NIH R01. Full-time appointment with initial one-year term and renewal based on satisfactory progress and continued funding. Salary range is $63,480-$71,748 annually, with University of Minnesota benefits.
Country
United States
University
University of Minnesota
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.
Apply for this position
Keywords
Suggested positions
About this position
NIH-funded postdoctoral positions are available in the Subramanian Laboratory in the Department of Surgery, University of Minnesota Medical School (Twin Cities campus, Minneapolis, Minnesota) to study colorectal cancer, malignant transformation, tumor immunology, extracellular vesicles, microRNA regulation, and adenoma-to-carcinoma progression.
The project asks how benign or premalignant colorectal adenomas acquire malignant properties and progress toward invasive cancer. A translational component evaluates engineered extracellular vesicles as a strategy to restore antitumor immunity and prevent malignant progression. Fellows may focus more on molecular mechanisms of adenoma transformation and organoid biology, or on extracellular vesicles, T-cell biology, and immune-mediated prevention.
Research methods include human and mouse colorectal adenoma models, organoids, CRISPR/Cas9, inducible gene expression, miRNA inhibitors, 2D/3D culture, spheroids, tumor-immune co-culture, flow cytometry, immune phenotyping, orthotopic and genetically engineered mouse models, inflammation-associated adenoma models, immunofluorescence/immunohistochemistry, RNA sequencing, and pathway analysis.
Applicants should hold a doctoral degree such as PhD, MD/PhD, or MD in a relevant biomedical field and have strong experimental training. Prior experience in colorectal cancer, organoid culture, extracellular vesicles, tumor immunology, or related techniques is preferred but not required if the candidate has a strong foundation and scientific independence.
The positions are full-time, supported by a recently funded NIH R01, and typically appointed for one year with renewal based on progress and funding. Salary is listed at $63,480-$71,748 annually, with University of Minnesota benefits.
To apply, submit a CV, cover letter, and three references to [email protected] and formally apply via the job portal. Optional PDFs or citations for up to three representative publications may also be included. In the cover letter, indicate whether your interests are strongest in malignant transformation, tumor immunology/extracellular-vesicle biology, or both.
Funding details
NIH-funded postdoctoral positions supported by a recently funded NIH R01. Full-time appointment with initial one-year term and renewal based on satisfactory progress and continued funding. Salary range is $63,480-$71,748 annually, with University of Minnesota benefits.
What's required
Applicants must have a PhD, MD/PhD, MD, or equivalent doctoral degree in cancer biology, molecular biology, cell biology, immunology, genetics, biochemistry, biomedical sciences, or a closely related field. Strong training in experimental biomedical research, hands-on experience in at least one relevant area, animal work and mammalian cell culture experience, and strong data analysis, troubleshooting, and scientific communication skills are required. Preferred experience includes colorectal or gastrointestinal cancer, organoid or spheroid culture, CRISPR/Cas9, microRNA, extracellular vesicles, tumor immunology, T-cell biology, flow cytometry, mouse cancer models, tumor-immune co-culture, molecular methods, and RNA-seq/bioinformatics.
How to apply
Submit a CV, cover letter, and names/contact information for three references to [email protected], and formally apply through the job posting. Optional representative publications may also be included. Indicate in the cover letter whether your interests are strongest in malignant transformation, tumor immunology/extracellular-vesicle biology, or both.
More information can be found here
Ask ApplyKite AI
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.