Up to 30% off — ends 2 Aug
ONLY00h00m00s
Up to 30% off — ends 2 Aug
ONLY00h00m00s
Université de Lorraine
1 week ago
Postdoctoral fellowship in engineering hyper-recombinogenic Streptomyces strains for biosynthetic pathway diversification and discovery of novel bioactive molecules Université de Lorraine in France
Degree Level
Postdoc
Field of study
Molecular Biology
Funding
Full funding availableDeadline
Aug 30, 2026
Country
France
University
Université de Lorraine
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.
More information can be found here
Official Email
Keywords
Suggested positions
About this position
Postdoctoral fellowship at Université de Lorraine (Nancy, France) in the DynAMic Laboratory on engineering hyper-recombinogenic Streptomyces strains for biosynthetic pathway diversification and discovery of novel bioactive molecules.
This position is part of the DIAMS project (Diversification of the Specialized Metabolite Synthesis Arsenal in Streptomyces via Recombination Modulation). The project aims to exploit NucS-mediated recombination and DNA double-strand break repair to generate hyper-recombinogenic chassis strains, accelerate biosynthetic pathway evolution, and uncover new specialized metabolites with potential biotechnological applications.
The research combines microbial genetics, molecular biology, genomics, metabolomics, and bioinformatics. Planned activities include genetic manipulation of Streptomyces, mutant and engineered strain construction, conjugation experiments, whole-genome sequencing, identification of hybrid biosynthetic gene clusters, and non-targeted metabolomics using high-resolution mass spectrometry. The successful candidate will work closely with the PASM Structural Analysis and Metabolomics Platform, the ASIA analytical platform, and international collaborators in the European GRASP project.
Applicants should hold a PhD in microbiology, molecular biology, genetics, biotechnology, genomics, or a related field. Experience with bacterial genetics, actinobacteria, DNA repair and homologous recombination, comparative genomics, metabolomics, mass spectrometry, or omics bioinformatics is highly desirable. Skills in Linux, R, or Python are considered an asset.
The position is based in Nancy, France, with access to strong facilities in genomics, metabolomics, and bioinformatics. The expected start date is October 2026, with some flexibility. Salary starts at about €2,000 gross per month depending on experience. Some fully funded mobility within the GRASP consortium is expected in mid-2027.
Applications are due by 2026-08-30 and must be sent by email to Dr Claire Bertrand together with a cover letter, CV and publication list, and academic transcripts.
Funding details
Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.
How to apply
Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.
Ask ApplyKite AI
How do I apply for this?
Sign in for free to reveal details, requirements, and source links.