Hospital del Mar
1 week ago
Postdoctoral Position in NK Cell Immunotherapy for Cancer at Hospital del Mar Research Institute Hospital del Mar Research Institute in Spain
Degree Level
Postdoc
Field of study
Immunology
Funding
Postdoctoral position for 1 year, extendable to 2 years. No stipend amount or tuition details mentioned.
Deadline
Oct 31, 2026
Country
Spain
University
Hospital del Mar

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About this position
Postdoctoral position in NK cell immunotherapy for cancer at Hospital del Mar Research Institute in Barcelona, in collaboration with the Institut de Biotecnologia i de Biomedicina (IBB), Universitat Autònoma de Barcelona (UAB).
The project is led by Dr. Aura Muntasell and focuses on developing an off-the-shelf, allogeneic TAR-NK cell product for cancer immunotherapy. The work sits at the interface of NK-cell biology, cell therapy manufacturing, and clinical translation.
Key research tasks include developing and standardizing the manufacturing process for SMAD4-edited human NK cells (expansion, CRISPR/Cas9 genetic modification, cryopreservation), transferring and manufacturing the clinical product with the Banc de Sang i Teixits de Catalunya, and supporting preclinical studies for IMPD submission (pharmacokinetic/pharmacodynamic, biodistribution, and efficacy studies in colorectal cancer models). The role also includes optimizing assays for identity, purity, safety, and potency of the final NK-cell product.
Applicants should have a PhD in Immunology, Cell Biology, Biotechnology, Biomedical Sciences, or a related field. Required experience includes primary human NK cell isolation and culture, multiparametric flow cytometry, immunological assays, NK-cell biology, experimental design, data analysis, troubleshooting, and English proficiency. GMP cell therapy manufacturing, CRISPR/Cas9 or electroporation, xenograft/PDX/humanized mouse models, CMC development, IMPD preparation, reporting, or project coordination are considered advantages.
The position is based in Barcelona, Spain, lasts 1 year and is extendable to 2 years. No funding amount is stated. To apply, send your updated CV and optional references to [email protected] before the end of October 2026.
Funding details
Postdoctoral position for 1 year, extendable to 2 years. No stipend amount or tuition details mentioned.
What's required
PhD in Immunology, Cell Biology, Biotechnology, Biomedical Sciences or a related field. Experience with primary human NK cell isolation and culture, multiparametric flow cytometry, and immunological assays is required. Knowledge of NK-cell biology, expansion and functional assays, ability to design experiments, analyze data, troubleshoot independently, and English proficiency are required. GMP-compliant cell therapy manufacturing, genetic modification of primary cells (electroporation or CRISPR/Cas9), xenograft/PDX/humanized mouse models, CMC development, IMPD preparation, scientific reporting, or project coordination are advantageous; GMP or clinical cell therapy experience is not essential.
How to apply
Send an updated CV and optional references by email to [email protected]. Apply before the end of October 2026.
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