Ruth Brenk
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Postdoctoral Research Fellow at the Department of Biomedicine University of Bergen in Norway
Degree Level
Postdoc
Field of study
Chemistry
Funding
Available
Deadline
Sep 30, 2026
Country
Norway
University
University of Bergen
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About this position
Postdoctoral Research Fellow in Structural Biology and Structure-Based Drug Design at the Department of Biomedicine, University of Bergen, Norway.
This full-time, three-year postdoctoral position is part of the eHACS project, financed by the Research Council of Norway, with the possibility of extension to four years subject to additional funding. The successful candidate will join the Brenk lab, which works in structure-based drug design, and contribute to experimental evaluation of designed compounds against the targets FabF, PanK, and NMT. The project combines protein expression and purification, binding studies using label-free biophysical methods, biochemical enzyme assays, and crystallographic analysis of protein-ligand complexes to guide compound design.
Key responsibilities include protein expression and purification, ligand-binding determination using methods such as BLI, SPR, or GCI, enzyme activity assays, crystal structure determination of target-ligand complexes, and structure-guided analysis to support medicinal chemistry and compound optimisation. The role is well suited to candidates with a strong background in structural biology and drug discovery-oriented experimental methods.
Eligibility requires a Norwegian PhD or equivalent degree in structural biology, or a doctoral thesis submitted before the deadline, with the PhD awarded no later than five months after the closing date. Applicants must have relevant hands-on experience with label-free biophysical methods for small-molecule binding, protein-ligand structure determination in a structure-based drug design context, and protein expression/purification of at least one of the named targets. Strong written and spoken English is required; experience with biochemical activity assays is an advantage. The university also emphasises independence, structured working style, and teamwork.
The appointment is based in Bergen, at the University of Bergen, and offers salary at NOK 690,000 in the state salary scale, alongside pension enrolment and welfare benefits. The deadline for applications is 30 September 2026 at 23:59 (Europe/Oslo). Applicants must submit a motivation statement, transcripts and diplomas, proof of the submitted doctoral thesis, a complete publication list, full copies of selected publications, and two references.
Funding details
Available
What's required
Applicants must hold a Norwegian PhD or an equivalent degree within structural biology, or have the doctoral thesis submitted before the application deadline. The PhD must be awarded no later than 5 months after the closing date. Required experience includes label-free biophysical methods such as BLI, SPR, or GCI for binding studies of small molecules to proteins, structure determination of protein-ligand complexes in a structure-based drug design context, and protein expression and purification of at least one target protein (FabF, PanK, or NMT). Proficiency in written and oral English is required. Experience with biochemical activity assays is an advantage. The candidate must be able to work independently, in a structured manner, and cooperate well with others.
How to apply
Apply through the Jobbnorge application portal using the official vacancy link. Include a motivation letter, transcripts and diplomas, documentation of the submitted doctoral thesis, a complete publication list, full PDFs of key publications, and two references with contact details. Submit any required supporting documents before the deadline.
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