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Masaryk University

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Postdoctoral Research Fellow in Non-Coding Genome Research Group: NMR of G-quadruplexes and i-Motifs Masaryk University in Czech Republic

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Full-time contract with an attractive salary. The position includes access to CEITEC MU core facilities, high-field NMR spectrometers, flexible working hours, occasional home office, and a seed funding opportunity with the possibility to apply for additional grants such as MSCA and EMBO. Benefits include 6 weeks of paid holiday, medical insurance, meal contribution, kindergarten/pension scheme, Multisport card, and mental health care.

Deadline

Oct 31, 2026

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Country

Czech Republic

University

Masaryk University

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Keywords

Biochemistry
Chemistry
Biomedical Engineering
Biophysics
Biology
Structural Biology
Nmr Spectroscopy
Nucleic Acid Chemistry
Physics

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About this position

Masaryk University / CEITEC in Brno is advertising a Postdoctoral Research Fellow position in the Non-Coding Genome Research group led by Lukáš Trantírek. The project sits at the intersection of structural biology, biophysics, chemistry, and biochemistry, with a strong focus on biomolecular NMR spectroscopy of nucleic acids.

The research will develop NMR methodologies to study the conformational landscapes of G-quadruplexes and i-motifs in DNA/RNA. The work includes ¹⁹F NMR and complementary biophysical assays to investigate structural equilibrium, dynamics, and ligand/peptide binding interactions in vitro and in the intracellular space. This is a strong fit for candidates interested in non-canonical nucleic acid structures, gene regulation, and translational structural biology.

Applicants should hold a PhD or equivalent in structural biology, chemistry, biochemistry, biophysics, or a related field. The ideal candidate has expertise or strong interest in biomolecular NMR, a strong publication record, and the ability to work independently while collaborating in a team. Helpful additional experience includes nucleic acid labeling strategies and biophysical methods such as ITC, MST, or BLI.

The position is full-time with an attractive salary and access to CEITEC MU core facilities, including high-field NMR spectrometers (600, 700, 850, and 950 MHz). The package also mentions flexible working hours, occasional home office, seed funding, support for further grants (including MSCA and EMBO), and extensive employee benefits.

Deadline: 31 October 2026. Start date: negotiable, preferably as soon as possible, expected January 2027. Apply through the online e-application form with a CV, publication list, motivation letter, and contact details for at least three references.

Funding details

Full-time contract with an attractive salary. The position includes access to CEITEC MU core facilities, high-field NMR spectrometers, flexible working hours, occasional home office, and a seed funding opportunity with the possibility to apply for additional grants such as MSCA and EMBO. Benefits include 6 weeks of paid holiday, medical insurance, meal contribution, kindergarten/pension scheme, Multisport card, and mental health care.

What's required

A PhD degree or equivalent in structural biology, chemistry, biochemistry, biophysics, or a related field is required. Applicants should have expertise or strong interest in biomolecular NMR, a strong publication record in peer-reviewed journals, and the ability to work independently while collaborating and learning in the lab. Nice-to-have experience includes nucleic acid labeling strategies (chemical, enzymatic synthesis, click chemistry basics), complementary biophysical assays such as ITC, MST, or BLI, and good communication and interpersonal skills.

How to apply

Submit an application via the online e-application form with a CV, publication list, motivation letter, and contact information for at least three references. For technical issues with the e-application, contact Darja Horáková at [email protected].

More information can be found here

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