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University College Dublin

Postdoctoral Researcher in Chromatin Mechanisms in Disease and H2AK119ub1 at University College Dublin University College Dublin in Ireland

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Temporary 18-month postdoctoral position funded through a Wellcome Trust award. Salary is €47,273-€53,925 per annum for PD1 and €55,399-€60,250 per annum for PD2, depending on qualifications and experience.

Deadline

Oct 19, 2026

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Country

Ireland

University

University College Dublin

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Keywords

Biochemistry
Computer Science
Chemistry
Biomedical Engineering
Cancer Biology
Biology
Computational Biology
Functional Genomics
Neuropsychology
Medical Science
Chromatin Biology
Neurodevelopmental Disorders
Histone Modification
Rna-seq
Epigenetic

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About this position

University College Dublin is advertising a temporary 18-month Post-doctoral Researcher Level 1 or 2 position in the School of Biomolecular and Biomedical Science, in the Chromatin Mechanisms in Disease laboratory led by Dr. Eric Conway.

The project focuses on chromatin biology, epigenetics, and the disease mechanisms underlying dysregulation of the repressive histone modification H2AK119ub1. The work will investigate how pathogenic variants in the PRC1 and PR-DUB complexes affect histone regulation in cancer and neurodevelopmental disease model systems.

Research methods include functional genomics, biochemistry, and proteomics, with techniques such as CUT&Tag, Captify, RNA-seq, immunoprecipitation followed by mass spectrometry, and high-throughput pooled CRISPR screens. The role may be computational biology, wet-lab, or a hybrid, depending on the successful candidate’s expertise.

This post is funded by a Wellcome Trust award. Salary is listed at €47,273–€53,925 per year for PD1 and €55,399–€60,250 per year for PD2, with appointment depending on qualifications and experience.

Eligibility highlights: PD1 is aimed at early-stage researchers, typically just after PhD completion or moving into a new area; applicants whose total postdoctoral experience would exceed 4 years should not apply. PD2 is for researchers who have completed PD1; applicants whose total postdoctoral experience would exceed 6 years should not apply.

The closing date is 19 October 2026 at 12:00 noon local Irish time. Applicants are instructed to use the Apply button on the vacancy page for further details and submission.

Funding details

Temporary 18-month postdoctoral position funded through a Wellcome Trust award. Salary is €47,273-€53,925 per annum for PD1 and €55,399-€60,250 per annum for PD2, depending on qualifications and experience.

What's required

Applicants should have completed a PhD for PD1-level consideration or have prior postdoctoral experience for PD2-level consideration. PD1 is intended for early-stage researchers just after PhD or entering a new area; applicants whose total postdoctoral experience including the advertised post would exceed 4 years should not apply. PD2 is intended for researchers who have completed PD1; applicants whose total postdoctoral experience including the advertised post would exceed 6 years should not apply. The role may be computational biology, wet-lab, or hybrid depending on expertise.

How to apply

Click the Apply button on the vacancy page for further details and submit the application before the deadline. Applications must be completed by 12:00 noon local Irish time on 19 October 2026.

More information can be found here

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