Postdoctoral Researcher in HIV-1 Innate Sensing, Lipid Metabolism and Dendritic Cell Biology Institut Imagine in France

Institut Imagine / INSERM / Université Paris Cité is recruiting a Postdoctoral Researcher for a project at the intersection of HIV-1, innate immunity, lipid metabolism, and dendritic cell biology.

The position is based in Paris, France, within the Single-Cell Inflammatory Responses & Multi-OMICs Networks (SCInflaNet) lab at Institut Imagine (Necker Hospital campus). The project builds on recent findings linking HIV-1 infection, lipid metabolic pathways, and type I interferon production in human dendritic cells.

The successful candidate will investigate how lipid metabolism regulates HIV-1 sensing and antiviral immunity. Research tasks include characterizing HIV-1-induced changes in lipid metabolism in human dendritic cells, testing how lipid pathways affect viral replication and interferon responses, and using lipidomics, scRNA-seq, scATAC-seq, and computational/systems biology approaches.

Eligibility highlights include a PhD in Immunology, Virology, Cell Biology, or a related field, experience with primary human immune cells (DCs, macrophages, PBMCs), and practical skills in flow cytometry, qPCR, Western blot, and CRISPR. A strong publication record and excellent English are expected. Experience with HIV/retrovirology, BSL-3 work, lipidomics, single-cell omics, and programming/analysis tools such as R, Python, Seurat, and Scanpy is a plus.

The appointment is for 2 years, renewable, with a competitive salary. The lab offers access to advanced platforms and a vibrant international environment, including single-cell genomics, flow cytometry, imaging, bioinformatics, BSL-3 facilities, mentoring, career development, conference support, and grant-writing training.

To apply, send a single PDF to [email protected] with a cover letter, CV with publication list, research summary, and contact information for 2–3 referees. Use the subject line Postdoc Application – LIPID- [Your Name].