Publisher
source

Karolinska Institutet

Postdoctoral Researcher in Single-Cell and Spatial Omics of CNS Development and Disease Karolinska Institutet in Sweden

Degree Level

Postdoc

Field of study

Computer Science

Funding

Fixed-term full-time employment for two years with a possibility of extension. Salary is set individually according to KI collective agreements; no stipend amount is stated.

Deadline

Oct 26, 2026

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Country

Sweden

University

Karolinska Institutet

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Keywords

Computer Science
Biology
Stem Cell Biology
Computational Biology
Neuropsychology
Medical Science
Omics
Brain Tumor
Statistics
Bioinformatic
Spatial Transcriptomic

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About this position

Postdoctoral Researcher in single-cell and spatial omics of CNS development and disease at Karolinska Institutet in Sweden.

The Li Research Group studies how the human central nervous system develops, how these programs are disrupted by injury and disease, and how they may be harnessed for regeneration and repair. The project sits at the intersection of neuroscience, medical science, single-cell omics, spatial transcriptomics, multi-omics, and computational biology.

The postdoctoral researcher will analyse single-cell and single-nucleus RNA-seq, spatial transcriptomics, and related omics datasets from human and rodent CNS development, brain tumors, and organoid models. The role includes integrating large datasets across developmental stages, anatomical regions, experimental models, and disease conditions; identifying cell states and developmental trajectories; and developing computational approaches for data integration, predictive modelling, gene-regulatory analysis, and cell-fate inference.

This is a full-time, fixed-term employment for two years with a possibility of extension. The position is located in Solna. Salary is set individually according to KI collective agreements. No scholarship or stipend is mentioned.

Eligibility requires a PhD or equivalent foreign degree by the time of the employment decision. Strong experience in single-cell or single-nucleus RNA-seq, spatial omics, R and/or Python, and reproducible computational workflows is required. Experience with multi-omics, chromatin accessibility, machine learning, perturbation analysis, CNS development, stem cell biology, brain tumors, or organoid research is considered an advantage.

To apply, prepare the required documents in English or Swedish: PhD certificate, complete CV, publication list, and a one-page summary of current work. Submit the application through the Varbi recruitment system before the deadline.

Application deadline: 2026-10-26.

Funding details

Fixed-term full-time employment for two years with a possibility of extension. Salary is set individually according to KI collective agreements; no stipend amount is stated.

What's required

Applicants must have a PhD or equivalent foreign degree by the time of the employment decision. Required experience includes analysing single-cell or single-nucleus RNA-seq data, spatial transcriptomics or other spatial omics data, and handling large complex biological datasets. Strong programming skills in R and/or Python are required, along with experience in quality control, cell-type annotation, differential analysis, data integration, and biological interpretation. Good English communication skills and the ability to collaborate with experimental biologists are expected. Experience with multi-omics, chromatin accessibility, gene-regulatory network analysis, trajectory or cell-fate modelling, machine learning, perturbation-data analysis, CNS development, stem cell biology, brain tumors, or organoid research is advantageous.

How to apply

Prepare the required documents in English or Swedish: PhD certificate, complete CV, complete publication list, and a one-page summary of current work. Submit the application through the Varbi recruitment system using the provided job portal link.

More information can be found here

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