University of Groningen
2 weeks ago
Three PhD positions in ML-guided directed evolution in biochemistry, molecular machine learning, and synthetic biology University of Groningen in Netherlands
Degree Level
PhD
Field of study
Computer Science
Funding
Three fully funded PhD positions for 4 years. Salary is at least €3,204 up to €4,051 gross per month for a full-time contract, with end-of-year bonus and holiday allowance. The post states a 1 year + 3 year employment structure.
Deadline
Oct 15, 2026
Country
Netherlands
University
University of Groningen

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About this position
Three fully funded PhD positions are available in the ML-GUIDE project on ML-guided directed evolution, combining deep learning, next-generation sequencing, synthetic chemistry, synthetic biology, and biomolecule engineering to accelerate the discovery of better (bio)catalysts and drugs.
The positions are hosted at the University of Groningen and the Technical University of Eindhoven (Netherlands), with candidates embedded in one of three research groups: the Artificial Organic Chemistry Lab (Dr. Robert Pollice), the Molecular Machine Learning Group (Prof. Francesca Grisoni), or the Molecular Evolution Group (Prof. Clemens Mayer). Research topics include peptide catalysts for C-C bond-forming reactions, cyclic-peptide drug design, and machine-learning-guided biocatalyst evolution.
This is a 4-year PhD opportunity with a salary of €3,204–€4,051 gross per month for full-time employment, plus holiday allowance and end-of-year bonus. The post specifies an MSc (or equivalent) in (Bio)chemistry, Biotechnology, Computational Chemistry, Synthetic Chemistry/Biology, or a related field. Experience in directed evolution, molecular machine learning, next-generation sequencing, or synthetic chemistry is preferred.
Deadline: 15 October 2026, 23:59 Dutch local time.
How to apply: Submit your application online with a motivation letter, CV, diplomas/transcripts, and two academic references. The vacancy page is the application portal.
Funding details
Three fully funded PhD positions for 4 years. Salary is at least €3,204 up to €4,051 gross per month for a full-time contract, with end-of-year bonus and holiday allowance. The post states a 1 year + 3 year employment structure.
What's required
Applicants need an MSc degree (or equivalent university degree) in (Bio)chemistry, Biotechnology, Computational Chemistry, Synthetic Chemistry/Biology, or a related field. Experience in directed evolution, molecular machine learning, next-generation sequencing, or synthetic chemistry is highly preferred. Candidates should be interested in interdisciplinary work at the interface of synthetic biology, molecular machine learning, and synthetic chemistry, and should have a research-oriented attitude with good analytical skills plus excellent communication and organization skills.
How to apply
Apply online via the vacancy page. Submit a motivation letter stating your key qualities and preferred ML-GUIDE research group, an up-to-date CV, diplomas and transcripts, and contact details of two academic references.
More information can be found here
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