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Clemens Mayer

2 weeks ago

Postdoctoral Researcher in Next-Gen Sequencing and Machine Learning for Directed Evolution University of Groningen in Netherlands

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Fully funded postdoctoral position supported by the ML-GUIDE consortium. Salary is €4,251 to €5,760 gross per month for a full-time contract under the Dutch university collective labor agreement. The appointment is temporary for 12 months with a possible extension of 24 months; holiday allowance, end-of-year bonus, and vacation hours are included.

Deadline

Sep 15, 2026

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Country

Netherlands

University

University of Groningen

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Keywords

Biochemistry
Computer Science
Machine Learning
Chemistry
Biomedical Engineering
Biology
Synthetic Biology
Chemical Biology
Biocatalysis
Next-generation Sequencing
Molecular Evolution
Directed Evolution
Bioinformatic

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About this position

Postdoctoral Researcher position at the University of Groningen in the Faculty of Science and Engineering, working within the ML-GUIDE consortium on next-generation sequencing, third-generation sequencing, machine learning, and directed evolution.

The project focuses on making directed evolution guidable and predictable by machine learning to accelerate the discovery of tailor-made (bio)catalysts and high-affinity binders for therapeutic targets and synthetic applications. The successful candidate will lead sequencing campaigns, generate data for active learning and Design-Build-Test-Learn cycles, and contribute to biomolecule engineering and molecular evolution research.

You will be embedded in the Molecular Evolution Group led by Prof. Clemens Mayer at the University of Groningen and collaborate closely with Prof. Francesca Grisoni and Dr. Robert Pollice. The broader research environment includes the Stratingh Institute for Chemistry, with strengths in bioorganic chemistry, organic chemistry, catalysis, functional materials, chemical biology, and systems chemistry.

This is a fully funded postdoctoral position with a salary of €4,251–€5,760 gross per month for full-time employment. The appointment is initially for 12 months with a possible 24-month extension. Additional benefits include vacation hours, an end-of-year bonus, and holiday allowance.

Eligibility highlights: a PhD (or equivalent) in (bio)chemistry, bioinformatics, synthetic chemistry/biology, or a related field; hands-on experience with next-generation sequencing libraries in directed evolution; strong English communication skills; and a strong publication record. Experience with third-generation sequencing or machine-learning integration is considered a plus.

Apply online by 15 September 2026 at 23:59 Dutch local time. Prepare a motivation letter, CV with publications, diplomas, and contact details for two academic references.

Funding details

Fully funded postdoctoral position supported by the ML-GUIDE consortium. Salary is €4,251 to €5,760 gross per month for a full-time contract under the Dutch university collective labor agreement. The appointment is temporary for 12 months with a possible extension of 24 months; holiday allowance, end-of-year bonus, and vacation hours are included.

What's required

Applicants must hold a PhD degree or equivalent university degree in (bio)chemistry, bioinformatics, synthetic chemistry/biology, or a related field. Required experience includes hands-on preparation and analysis of next-generation sequencing libraries in directed evolution. Third-generation sequencing experience or interfacing sequencing data with machine learning is a plus. Candidates should have a proven publication record in international peer-reviewed journals, strong English verbal and written communication skills, experience supervising BSc/MSc/PhD students as an advantage, and a proactive, motivated approach to research and teamwork.

How to apply

Apply online via the vacancy page before 15 September 2026 at 23:59 Dutch local time. Submit a motivation letter, up-to-date CV with publications, diplomas, and contact information for two academic references.

More information can be found here

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