Jeff Perry

Jeff Perry’s laboratory at the Beckman Research Institute of City of Hope is advertising a postdoctoral fellow position in drug discovery , structural biology , and metabolic disease . The project centers on a metabolic enzyme with a central role in cholesterol homeostasis and bile acid synthesis , with direct relevance to cardiometabolic risk and translational therapeutics. The successful candidate will lead work in recombinant protein expression and purification and X-ray crystallography to support structure-guided ligand design . The role sits at the interface of chemical biology , protein biochemistry , and drug discovery , contributing to the development of first-in-class modulators for a clinically relevant metabolic pathway. Required background: a Ph.D. in life sciences, biomedical sciences, or a related discipline; prior experience in protein biochemistry and X-ray crystallography; strong research output and publications; and excellent analytical, problem-solving, communication, and collaboration skills. Preferred experience: quantitative biophysical assays for small-molecule binding such as SPR , ITC , and DSF , plus interest in mechanism-driven and fragment-based drug discovery. Funding: this is a paid postdoctoral employee position at City of Hope. Compensation depends on experience, qualifications, and work location; no specific stipend or deadline is listed in the post. How to apply: the post does not include a direct application link or email address. Candidates should reach out through the lab or City of Hope recruitment channels for application instructions.