Jeff Perry
5 days ago
Postdoctoral Fellow in Structure-Guided Drug Discovery and Metabolic Enzyme Biology Beckman Research Institute of City of Hope in United States
Degree Level
Postdoc
Field of study
Chemistry
Funding
Postdoctoral employee position at City of Hope; pay is based on work experience, qualifications, and work location. No stipend amount or funding package is specified.
Country
United States
University
Beckman Research Institute, City of Hope
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About this position
Jeff Perry’s laboratory at the Beckman Research Institute of City of Hope is advertising a postdoctoral fellow position in drug discovery, structural biology, and metabolic disease. The project centers on a metabolic enzyme with a central role in cholesterol homeostasis and bile acid synthesis, with direct relevance to cardiometabolic risk and translational therapeutics.
The successful candidate will lead work in recombinant protein expression and purification and X-ray crystallography to support structure-guided ligand design. The role sits at the interface of chemical biology, protein biochemistry, and drug discovery, contributing to the development of first-in-class modulators for a clinically relevant metabolic pathway.
Required background: a Ph.D. in life sciences, biomedical sciences, or a related discipline; prior experience in protein biochemistry and X-ray crystallography; strong research output and publications; and excellent analytical, problem-solving, communication, and collaboration skills. Preferred experience: quantitative biophysical assays for small-molecule binding such as SPR, ITC, and DSF, plus interest in mechanism-driven and fragment-based drug discovery.
Funding: this is a paid postdoctoral employee position at City of Hope. Compensation depends on experience, qualifications, and work location; no specific stipend or deadline is listed in the post.
How to apply: the post does not include a direct application link or email address. Candidates should reach out through the lab or City of Hope recruitment channels for application instructions.
Funding details
Postdoctoral employee position at City of Hope; pay is based on work experience, qualifications, and work location. No stipend amount or funding package is specified.
What's required
Ph.D. in life sciences, biomedical sciences, or a related discipline is required. Prior experience in protein biochemistry and X-ray crystallography is essential. Experience with quantitative biophysical characterization of small-molecule binding studies such as SPR, ITC, and DSF is highly desirable, along with interest in mechanism-driven drug discovery and fragment-based approaches. Strong publication record, analytical/problem-solving skills, and effective communication/collaboration abilities are expected.
How to apply
No application portal or email is provided in the post. Interested candidates should contact the lab or monitor City of Hope careers/recruitment channels for the opening.
More information can be found here
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