Jens Schwamborn

PhD opportunity in Organoid Intelligence at the University of Luxembourg , Luxembourg Centre for Systems Biomedicine (LCSB), in the Developmental and Cellular Biology Group led by Prof. Jens Schwamborn . The project focuses on using human brain organoids as a living, adaptive computing substrate. The successful candidate will build a reservoir computing platform in which a human iPSC-derived brain organoid acts as the physical reservoir. Time-dependent inputs will be delivered as spatiotemporal electrical stimulation through a high-density multielectrode array (MEA) , and the resulting nonlinear network dynamics will be analyzed for computational tasks. This is a highly interdisciplinary PhD combining neuroscience , neurobiology , biophysics , biology , biomedical engineering , and computer science . The work includes organoid generation and long-term maintenance, MEA-based stimulation and recording, closed-loop training protocols, and analysis of activity-dependent plasticity, functional connectivity, learning, and memory in human neural tissue. Eligibility highlights: Master’s degree or equivalent in neuroscience, bioengineering, biology, biophysics, or a closely related field; hands-on MEA experience is required; strong background in neurobiology is preferred; experience with human stem cell biology and organoids is a strong advantage; Python or MATLAB and interest in machine learning/reservoir computing are welcome; B2-level language proficiency in the language of the thesis is required. Funding: fixed-term full-time doctoral contract for 24 months. The annual gross salary is EUR 43,445. How to apply: submit the application online via the University of Luxembourg HR system. Include a CV, motivation letter, transcript of university courses/results, and contact details for 1–2 referees. Applications are processed upon reception, so early submission is encouraged. Location: Belval Campus, Luxembourg.