Jens Schwamborn
2 months ago
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PhD in Organoid Intelligence, Brain Organoids and Reservoir Computing University of Luxembourg in Luxembourg
Degree Level
PhD
Field of study
Computer Science
Funding
Fixed-term full-time PhD position for 24 months. The yearly gross salary for every doctoral researcher at the University of Luxembourg is EUR 43,445 (full time).
Country
Luxembourg
University
University of Luxembourg

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About this position
PhD opportunity in Organoid Intelligence at the University of Luxembourg, Luxembourg Centre for Systems Biomedicine (LCSB), in the Developmental and Cellular Biology Group led by Prof. Jens Schwamborn.
The project focuses on using human brain organoids as a living, adaptive computing substrate. The successful candidate will build a reservoir computing platform in which a human iPSC-derived brain organoid acts as the physical reservoir. Time-dependent inputs will be delivered as spatiotemporal electrical stimulation through a high-density multielectrode array (MEA), and the resulting nonlinear network dynamics will be analyzed for computational tasks.
This is a highly interdisciplinary PhD combining neuroscience, neurobiology, biophysics, biology, biomedical engineering, and computer science. The work includes organoid generation and long-term maintenance, MEA-based stimulation and recording, closed-loop training protocols, and analysis of activity-dependent plasticity, functional connectivity, learning, and memory in human neural tissue.
Eligibility highlights: Master’s degree or equivalent in neuroscience, bioengineering, biology, biophysics, or a closely related field; hands-on MEA experience is required; strong background in neurobiology is preferred; experience with human stem cell biology and organoids is a strong advantage; Python or MATLAB and interest in machine learning/reservoir computing are welcome; B2-level language proficiency in the language of the thesis is required.
Funding: fixed-term full-time doctoral contract for 24 months. The annual gross salary is EUR 43,445.
How to apply: submit the application online via the University of Luxembourg HR system. Include a CV, motivation letter, transcript of university courses/results, and contact details for 1–2 referees. Applications are processed upon reception, so early submission is encouraged.
Location: Belval Campus, Luxembourg.
Funding details
Fixed-term full-time PhD position for 24 months. The yearly gross salary for every doctoral researcher at the University of Luxembourg is EUR 43,445 (full time).
What's required
Master’s degree or equivalent in neuroscience, bioengineering, biology, biophysics, or a closely related field. Hands-on experience with multielectrode array (MEA) technology is required, including stimulation, recording, and analysis of extracellular network activity. A solid background in neurobiology is expected, ideally including synaptic plasticity, long-term potentiation, and neural network dynamics. Experience with human stem cell biology and organoids such as iPSC culture, neural differentiation, and brain organoid generation is a strong asset. Familiarity with Python or MATLAB and interest in reservoir computing or machine learning are welcome. Applicants must demonstrate at least B2-level proficiency in the language of their thesis.
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