Kathryn Holt

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Professor (Research)

MONASH UNIVERSITY

Australia

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Professor Kathryn Holt is a faculty member in the Research department at Monash University, Australia. Her research encompasses a variety of areas including microbial genomics, antibiotic resistance, and public health genomics, as evidenced by her recent publications on topics such as antigen typing, the epidemiology of Shigella sonnei, and precision public health in the era of big data. Professor Holt is dedicated to advancing the understanding of bacterial pathogenesis and the genetic factors influencing resistance during infections.

Recent Grants

Grant: Close

Genomic Investigations of Antimicrobial Resistance

Open Date: 2018-01-01

Close Date: 2022-12-01

Grant: Close

Experimental co-evolution of Yeast and E. coli

Open Date: 2018-01-01

Close Date: 2020-12-01

Grant: Close

HHMI International Research Scholar

Open Date: 2017-10-01

Close Date: 2022-08-01

Grant: Close

Molecular networks and genomics of host response in typhoid fever

Open Date: 2016-01-01

Close Date: 2018-01-01

Grant: Close

Types of E. coli that cause diarrhoea

Open Date: 2014-01-01

Close Date: 2016-12-31

Kathryn Holt

Research Interests

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About

Recent Grants

Articles (19)

Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions

Fast and accurate in silico antigen typing with Kaptive 3

Genomic data sharing: you don’t know what you’ve got (till it’s gone)

Targeted sequencing of Enterobacterales bacteria using CRISPR-Cas9 enrichment and Oxford Nanopore Technologies

Precision public health in the era of genomics and big data

In vivo selection of carbapenem resistance during persistent Klebsiella pneumoniae sequence type 395 bloodstream infection due to OmpK36 deletion

A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex

Shigella Serotypes Associated With Carriage in Humans Establish Persistent Infection in Zebrafish

Acquisition of a large virulence plasmid (pINV) promoted temperature-dependent virulence and global dispersal of O96:H19 enteroinvasive Escherichia coli

Within–patient and global evolutionary dynamics of Klebsiella pneumoniae ST17

Comment on: MDR carbapenemase-producing Klebsiella pneumoniae of the hypervirulence-associated ST23 clone in Poland, 2009–19

Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing

Bactabolize is a tool for high-throughput generation of bacterial strain-specific metabolic models

Bactabolize is a tool for high-throughput generation of bacterial strain-specific metabolic models

Genomic population structures of microbial pathogens

Transmission of Klebsiella strains and plasmids within and between grey‐headed flying fox colonies

Detection of Klebsiella pneumoniae human gut carriage: a comparison of culture, qPCR, and whole metagenomic sequencing methods

Correction to: Diversity and evolution of surface polysaccharide synthesis loci in Enterobacteriales

Species interactions constrain adaptation and preserve ecological stability in an experimental microbial community

Collaborators (17)

Vincenzo Torraca

Ørjan Samuelsen

Mark Achtman

Wayne Boardman

Arnfinn Sundsfjord

Hugh Cottingham

Michael J. McDonald

Fiona McDougall

Guilherme Del Fiol

Kate Baker

Michelle Power

Iren H. Löhr

Stephen Baker

Kelly L Wyres

Sylvain Brisse

Yutaka Suzuki

Serge Mostowy

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