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Koyal Garg
Associate Professor
Research Interests
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Positions (1)
Saint Louis University
Saint Louis University
10 months ago
A postdoctoral position is available in the laboratory of Dr. Koyal Garg, Associate Professor in the Department of Biomedical Engineering at Saint Louis University (SLU), St. Louis, MO. The research focus is on biomaterials, tissue engineering, and cellular/molecular biology, with an emphasis on musculoskeletal tissues. The lab values teamwork, curiosity, and diversity, and offers a collaborative environment for independent research and professional development. This is a two-year, fully funded position with a starting stipend of $65,000 in the first year and a 3% merit increase in the second year, plus benefits and a travel allowance for conference presentations. Candidates should have a Ph.D. or be near completion in Biomedical Engineering or a related field, with experience in musculoskeletal tissues, molecular biology, mammalian cell culture, biomaterials, animal models, histology, and biochemical techniques. A strong publication record in peer-reviewed journals is required. Responsibilities include conducting independent research, contributing to ongoing projects, mentoring undergraduate and graduate students, upholding ethical research standards, assisting in grant proposals, and maintaining collegiality. Opportunities for classroom teaching and independent pursuit of fellowships and/or grant funding are available. Dr. Garg champions diversity and work-life balance, prioritizing the growth and success of her trainees through individualized mentorship and support. Interested candidates should send Dr. Koyal Garg ([email protected]) a brief description of their research interests, CV, and a list of three references. For more information, candidates are encouraged to visit the lab's website and review Dr. Garg's academic profile. The application deadline is July 1, 2026.
10 months ago
Articles (6)
Year:
2026
Year:
2025
Year:
2025
Year:
2025
Year:
2025
Volumetric muscle loss (VML) causes irrecoverable loss of muscle mass and strength and results in permanent disability. VML injury shows extensive fibrosis, which impedes functional tissue regeneration. Our lab has created a biosponge scaffold composed of extracellular matrix (ECM) proteins (i.e., biosponge) that can enhance muscle regeneration and function following VML. In this work, a potent small molecule inhibitor of alpha v-subunit containing integrins known as IDL-2965 was incorporated into the biosponges for localized suppression of fibrosis post-VML. Our results demonstrate that local delivery of IDL-2965 via the biosponges attenuated the deposition of fibrotic tissue preceded by a downregulation of profibrotic genes in VML-injured muscles. The reduction in fibrotic tissue had no detrimental effects on muscle mass, function, size, or vascularity. Overall, these findings suggest that the codelivery of biosponges and IDL-2965 is a safe and effective strategy for the mitigation of fibrotic tissue deposition in VML-injured muscles.
Year:
2023
Collaborators (2)
Chandrasekhar R. Kothapalli
Professor
Cleveland State University
Prabaha Sikder
Associate Professor
Cleveland State University
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