Vincent de Boer
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Assistant Professor
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Recent Grants
Grant: Close
VENI - Fighting energy crises with an anti-ageing enzyme
Open Date: 2010-01-01
Close Date: 2013-01-01
Grant: Close
Rubicon - The role of SIRT4 in aging and metabolism
Open Date: 2007-01-01
Close Date: 2009-01-01
Articles (15)
Functional and molecular profiling of fasted piglets reveals decreased energy metabolic function and cell proliferation in the small intestine
Fasting is identified as one of the underlying causes potentiating diarrhea development, both in piglets and humans. With this study, we demonstrate that fasting decreases the metabolism of intestinal epithelial cells, on a functional and transcriptional level. Transcriptional and histological data also show decreased intestinal cell proliferation. As such, fasting-induced intestinal energy shortage could contribute to intestinal dysfunction upon fasting.
Year:
2023
Collaborators (11)
Xavier Escoté
Universidad de Navarra
Anna Bekebrede
Wageningen University & Research
R.J.Joost van Neerven
Associate professor
Wageningen University & Research
Jaap Keijer
Wageningen University & Research
Riekelt Houtkooper
University of Amsterdam
Rubén Zapata-Pérez
Universidad Católica San Antonio de Murcia
Bart Lagerwaard
Universitair Medisch Centrum Utrecht
Thirza van Deuren
University of Maastricht
Rogier Versteeg
dept. head
Amsterdam UMC, University of Amsterdam
Mojtaba Porbahaie
Wageningen University & Research
Arie Nieuwenhuizen
Assistant professor
Wageningen University & Research
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