PhD in Automated Closed-Loop Peptide Drug Discovery to Replace Antibodies University of Warwick in United Kingdom

PhD opportunity at the University of Cambridge in RNA biology and machine learning . This Cambridge Biosciences BBSRC DTP PhD project will investigate how RNA modifications reshape RNA structure and function . The project is supervised by Bianca Pierattini and Eric Miska , and includes a Computer Science rotation in Pietro Lio'’s Lab . The research is highly interdisciplinary and combines RNA biology , structural probing , high-throughput sequencing , cell biology , computational modelling , and...

University of Manchester is advertising a Postdoctoral Research Associate in Polymeric Materials Modelling based in Manchester, England, United Kingdom . The project focuses on the molecular modelling of cellulose oligomers and the self-assembly of cellulose in the plant cell wall . The successful candidate will use a combination of machine learning , molecular dynamics simulations , and high-performance computing (including Isambard AI) to screen large arrays of cellulose-like structures with d...

PhD opportunity: Machine learning for finding macromolecules in cells at the Medical Research Council Laboratory of Molecular Biology (Cambridge, United Kingdom). This project combines machine learning , artificial intelligence , and structural biology to develop computer software for identifying macromolecular complexes in cryo-EM and cryo-electron tomography (cryo-ET) data collected from thinned human and budding yeast cells. The main biological target is the kinetochore , with methods intende...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences, focused on β-lactamase-mediated antibiotic resistance , biomolecular simulation , enzyme kinetics , and X-ray crystallography . The project investigates how class C β-lactamases break down cephalosporin antibiotics and how diazabicyclooctanone (DBO) inhibitors block these enzymes. The research combines computational chemistry, structural biology, molecular biology/biochemistry, and kinetic expe...

PhD opportunity at the Radcliffe Department of Medicine, University of Oxford in Oxford, United Kingdom . This project, Mapping and Editing Gene Regulatory Networks to Develop Therapies for Genetic Disorders , focuses on genomics , human genetics , molecular genetics , functional genomics , cell biology , and genetic engineering . The research aims to understand how inherited diseases can arise from variants in regulatory DNA rather than only from mutations in protein-coding genes. The student w...