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Princess Máxima Center for Pediatric Oncology

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PhD in Human Liver Organoids, CRISPR-Cas and MASLD at the Princess Máxima Center Princess Máxima Center for Pediatric Oncology in Netherlands

Degree Level

PhD

Field of study

Metabolism

Funding

4-year PhD project funded by a Vidi grant from the Dutch Research Council (NWO). Temporary full-time position for 36 hours/week, initially for 1 year with possible extension for the remaining years. Gross monthly salary is FWG 45-6 and includes 8.33% holiday allowance and 8.33% end-of-year bonus.

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Country

Netherlands

University

Princess Máxima Center for Pediatric Oncology

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Keywords

Metabolism
Biomedical Engineering
Biology
Medical Science
Pediatric Oncology
Liver Physiology

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About this position

PhD position in the Artegiani & Hendriks group at the Princess Máxima Center for Pediatric Oncology in Utrecht, Netherlands.

This project focuses on human liver function and disease, with an emphasis on metabolic dysfunction associated steatotic liver disease (MASLD), liver metabolism, and mechanisms that may contribute to liver cancer. The research uses human organoids, CRISPR-Cas tools, single-cell RNA sequencing, and advanced imaging to study liver biology in relevant in vitro models.

The position is a 4-year PhD project funded by a Vidi grant from the Dutch Research Council (NWO). It is a full-time temporary appointment (36 hours/week), initially for 1 year with possible extension. Salary is stated as FWG 45-6, including holiday allowance and end-of-year bonus.

Applicants should have recently completed an MSc and have a background in molecular biology, cellular biology, stem cell biology, and/or developmental biology. Experience with bioinformatic tools or advanced imaging is a plus. The work language is English, and the group/institute is described as international and multidisciplinary.

To apply, upload a CV, a short motivation letter (maximum two pages), and contact details for 2-3 references via the AFAS portal. The vacancy remains open until a suitable candidate is found, and review starts as soon as possible.

Funding details

4-year PhD project funded by a Vidi grant from the Dutch Research Council (NWO). Temporary full-time position for 36 hours/week, initially for 1 year with possible extension for the remaining years. Gross monthly salary is FWG 45-6 and includes 8.33% holiday allowance and 8.33% end-of-year bonus.

What's required

Recently completed an MSc degree. Background in molecular biology, cellular biology, and/or stem cell and developmental biology is required. Experience with bioinformatic tools or advanced imaging is considered a plus. The candidate should be highly motivated, committed, able to work independently, and comfortable in a multidisciplinary and international research environment; English is the work language.

How to apply

Apply through the AFAS portal by uploading your CV, a short motivation letter (maximum two pages), and contact details for 2-3 references. Incomplete applications will not be considered. For questions, contact Delilah Hendriks.

More information can be found here

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