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University of St Andrews

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PhD in Mechanisms of Pulsed Contractions During Drosophila Morphogenesis University of St Andrews in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Competition-funded 4-year PhD studentship through EASTBIO BBSRC Doctoral Training Partnership. Open to UK and international students. Funding covers a stipend at the UKRI standard rate and UK-level tuition fees; the University of St Andrews covers the Home-International fee difference.

Deadline

Nov 16, 2026

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Country

United Kingdom

University

University of St Andrews

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Keywords

Cell Biology
Molecular Biology
Biology
Optogenetics
Genetic

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About this position

PhD opportunity in Drosophila morphogenesis, cell contractility, and developmental biology at the University of St Andrews. This EASTBIO-funded project investigates the mechanisms underlying pulsed contractions during morphogenesis, with a focus on how rhythmic cytoskeletal contractility drives apical constriction and tissue shaping in Drosophila larval epithelial cells.

The project combines cell biology, genetics, and molecular biology with advanced imaging and manipulation approaches. You will use analogue-sensitive alleles of contractility regulators and develop optogenetic tools to modulate contractility at the subcellular level and within individual cells in a tissue. The work will use state-of-the-art 4D microscopy and quantitative image analysis to study how local and tissue-level perturbations affect pulsed contractions.

You will be based at the University of St Andrews and work across two complementary labs: the Bischoff lab in St Andrews, which has expertise in Drosophila morphogenesis and pulsatile cytoskeletal activity, and the Januschke lab in Dundee, which develops tools for targeted manipulation of cell contractility. The project offers a collaborative research environment and training opportunities through taught courses and transferable skills development.

Funding: This is a 4-year competition-funded PhD studentship. It is open to UK and international students and provides a stipend at the UKRI standard rate plus UK-level tuition fees; the Home-International fee difference is covered by the University of St Andrews.

Eligibility and application: Applicants should be prepared to submit academic qualifications, references, and an English language qualification if applicable. The application requires completion of the EASTBIO Equality, Diversity and Inclusion survey, the EASTBIO Application Form, and an online application through the University of St Andrews portal. Select the course PhD with internship.

Deadline: Monday, 16 November 2026.

Funding details

Competition-funded 4-year PhD studentship through EASTBIO BBSRC Doctoral Training Partnership. Open to UK and international students. Funding covers a stipend at the UKRI standard rate and UK-level tuition fees; the University of St Andrews covers the Home-International fee difference.

What's required

Applicants should be interested in cell biology, genetics, and molecular biology, with an ability to work on Drosophila morphogenesis, live imaging, quantitative image analysis, and experimental manipulation of contractility. The project mentions English language qualification if applicable and requires two references plus academic qualifications as part of the application.

How to apply

Download and complete the EASTBIO Equality, Diversity and Inclusion survey and the EASTBIO Application Form. Submit an online application via the University of St Andrews portal and select the course 'PhD with internship'. Include the EASTBIO form, academic qualifications, English language qualification if applicable, and two references on the EASTBIO Reference Form.

More information can be found here

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