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University of Luxembourg

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PhD in Microbial Metabolites, Immunometabolism, and T-Cell Lipid Pathways (UNLIMITED MSCA Doctoral Network) University of Luxembourg in Luxembourg

Degree Level

PhD

Field of study

Metabolism

Funding

Full funding available
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Country

Luxembourg

University

University of Luxembourg

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Keywords

Metabolism
Inflammation
Biology
Medical Science
Immune Response
Microbiome Research
Immunometabolism
Lipidomic

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About this position

PhD opportunity in microbial metabolites, immunometabolism, lipidomics, and T-cell biology within the UNLIMITED Marie Skłodowska-Curie Actions Doctoral Network (MSCA-DN). The project, DC 14 – Microbial Metabolites as Immune Metabolic Switches: Rewiring Lipid Pathways to Shape T-Cell Function, is hosted by the Luxembourg Institute of Health with PhD enrolment at the University of Luxembourg.

The research aims to define how microbiome-derived and tissue-derived metabolites control lipid metabolism in T cells and shape immune function. The candidate will screen metabolites for effects on T-cell metabolism and differentiation, characterize metabolite-induced lipid remodeling using advanced lipidomics and single-cell metabolic profiling, identify pathways with CRISPR/Cas9 perturbation, and validate findings in human systems and preclinical inflammation models.

Methods mentioned include state-of-the-art lipidomics, SCENITH, Met-Flow, CRISPR/Cas9 genome editing, and functional immunometabolic assays. Planned secondments include the Laura Bindila lab at the University Medical Center of Mainz for lipidomics and quantitative assays, and the ActiTrexx lab with Dr. Helmut Jonuleit in Mainz for human T-cell models and validation of therapeutic targets.

This is a fully funded PhD position under an EU MSCA Doctoral Network. The post states a 36-month duration and a start at M6. No application deadline or stipend amount is provided in the post.

Ideal for candidates interested in immunology, microbiome research, metabolism, lipidomics, and CRISPR-based functional studies. Apply via the project link and follow the recruitment instructions for Project #14.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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