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Cardiff University

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PhD in Multi-omics, Proteomics, and Glioblastoma Stem Cell Therapy Resistance Cardiff University in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

Competition-funded PhD project through the GW4 BioMed3 MRC Doctoral Landscape Programme. Funding includes UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available. Open to UK and international applicants.

Deadline

Oct 21, 2026

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Country

United Kingdom

University

Cardiff University

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Keywords

Cell Biology
Computer Science
Molecular Biology
Biomedical Engineering
Cancer Biology
Biology
Neuropsychology
Medical Science
Proteostasis
Omics
Genomic
Statistics
Bioinformatic

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About this position

PhD opportunity at Cardiff University in the Cardiff School of Biosciences on glioblastoma stem cells, multi-omics, proteomics, protein turnover, and therapy resistance.

The project asks how glioblastoma stem cells evade therapy and drive tumour recurrence, with a focus on how FGF2-FGFR1 signalling regulates protein homeostasis and how the downstream ZEB1-HECTD4 axis may control proteostasis and stemness. The work combines computational and experimental approaches, including analysis of existing single-cell and bulk sequencing datasets, kinome profiling, patient-derived GBM models, proteomic analysis, and functional assays.

Research themes and keywords include cancer biology, bioinformatics, genomics, cell biology, molecular biology, and neuroscience. The student will help identify candidate genes and proteins, validate targets in human patient-derived GBM cell lines, and contribute to discovering new therapeutic opportunities for brain cancer.

Eligibility: applicants should have, or expect to obtain, a first or upper second-class UK honours degree (or equivalent). English requirement: IELTS 6.5 overall with 5.5 in all subskills, or an acceptable alternative.

Funding: fully funded competition studentship via the GW4 BioMed3 MRC Doctoral Landscape Programme, covering UK tuition fees and a stipend of £21,805 p.a. for 2026/27, plus up to £5,000 per year in additional research training/support funding. Open to UK and international applicants.

Application: apply via the GW4 BioMed website, choose up to two projects, and submit one application per candidate. If shortlisted, interview invitations are expected from 22 December 2026, with virtual interviews on 26–27 January 2027. The studentship is scheduled to start on 1 October 2027.

Funding details

Competition-funded PhD project through the GW4 BioMed3 MRC Doctoral Landscape Programme. Funding includes UK tuition fees and a Doctoral Stipend matching the UK Research Council National Minimum (£21,805 p.a. for 2026/27, updated annually). Additional research training and support funding of up to £5,000 per annum is available. Open to UK and international applicants.

What's required

Applicants must have obtained, or be about to obtain, a first or upper second-class UK honours degree, or an equivalent qualification gained outside the UK. English language requirement: IELTS overall 6.5 with 5.5 in all subskills, or an acceptable alternative.

How to apply

Review the GW4 BioMed website for the full list of projects and application instructions. Select up to 2 projects and submit one application per candidate only. Apply for an 'offer of funding' through GW4 BioMed3, and if shortlisted you will later need to apply for an 'offer to study' at the chosen institution.

More information can be found here

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