PhD in Peptide Activation of TFEB for Neurodegeneration University of Bath in United Kingdom

PhD opportunity in Structure-Function Analysis of Stress Signaling at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with supervision by Dr A Bertolotti. The lab studies stress signaling and the integrated stress response (ISR), with a strong focus on how cells protect themselves from misfolded proteins and how these pathways may be harnessed to improve resilience in disease. The project is especially relevant to neurodegenerative diseases such as Alzheimer’s disease,...

King’s College London is advertising a Postdoctoral Research Associate position in structural biology and neurodegeneration , based at the Guy’s and Denmark Hill campuses in London . The project will investigate how Annexin A11 interactions are regulated and disrupted in neurodegeneration and ALS/MND . The work is part of an MND Association-supported research project and combines NMR , SAXS , and cell biology , with collaborations involving the Università degli Studi di Torino and the UK Dementi...

PhD opportunity in Protein Aggregates and Neurodegeneration at the Medical Research Council (Cambridge), Laboratory of Molecular Biology, with Dr H McMahon. This project explores how protein aggregates accumulate, become toxic to brain cells, and spread in neurodegenerative disease. Two related PhD projects are available in the McMahon group. One focuses on aggregate uptake mechanisms , including Aggregation-Dependent Endocytosis, receptor identification, aggregate size effects, and ways to prev...

PhD opportunity in pathological protein assembly in neurodegenerative diseases at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom . The project is centered on the molecular pathology of neurodegeneration, with a focus on amyloid filament formation by disease-associated proteins such as TDP-43 , annexin A11 , and TAF15 . Two PhD project directions are described. One aims to reproduce pathological protein filament structures in vitro using protein biochemist...

Weill Cornell Medicine is advertising a Postdoctoral Associate in Biochemistry & Biophysics in the Reck-Peterson Lab , focused on the mechanisms of intracellular transport across molecular, cellular, and organismal scales. The project areas include: (1) how defects in intracellular transport contribute to neurodegenerative disease , with emphasis on LRRK2 and Parkinson’s disease ; (2) mechanisms of organelle “hitchhiking” in filamentous fungi and their implications for secondary metabolite produ...