PhD in Synaptic Mechanisms of Prediction-Error Plasticity in Neuroscience University of St Andrews in United Kingdom

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on cerebral small vessel disease (cSVD) , with a focus on identifying shared mechanisms and therapeutic targets across genetic and sporadic disease forms. The project will use patient-derived induced pluripotent stem cell (iPSC) models to study vascular cell phenotypes in the neurovascular unit. The research combines cellular biology , molecular biology , functional assays , and transcriptomics/omics to un...

PhD opportunity in Neuroscience, Molecular Biology, and Behavioural Biology at the Medical Research Council (Cambridge), Laboratory of Molecular Biology. This project, supervised by Dr Marco Tripodi, investigates how the brain transforms perception into action. The research focuses on neural circuits linking the motor cortex, thalamus, and superior colliculus, with particular interest in genetically defined Pitx2 neurons and their role in sensorimotor transformation, intention, movement preparat...

PhD opportunity at the University of St Andrews in the School of Psychology and Neuroscience on descending and ascending control of locomotor and respiratory central pattern generators (CPGs) in health and disease . This project sits at the intersection of neuroscience , neurology , cell biology , and molecular biology , with a strong focus on motor control, respiratory control, and disease-relevant circuit mechanisms. The research will investigate how supraspinal descending pathways and ascendi...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on programmed axon death , SARM1 , NMNAT2 , and protein design . The project focuses on understanding the mechanism of programmed axon death, an intrinsic axonal death pathway implicated in neurodegenerative disease and injury. The work will use rational protein design to create variant forms of SARM1 or hybrid reporter constructs to study activation, stability, enzyme activity, and post-translational modi...

PhD opportunity in neuroscience , molecular biology , and behavioural biology at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom . The project, supervised by Dr Marta Zlatic , focuses on the circuit basis of learning and action selection in the tractable Drosophila larva . The research aims to uncover how distributed brain circuits implement memory formation and action choice using a synaptic-resolution connectome, genetic tools, and functional experimen...