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University of St Andrews

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PhD in Descending and Ascending Control of Locomotor and Respiratory Central Pattern Generators in Health and Disease University of St Andrews in United Kingdom

Degree Level

PhD

Field of study

Cell Biology

Funding

This is a 4-year competition-funded PhD project through the EASTBIO BBSRC Doctoral Training Partnership. It is open to UK and international students and provides a stipend at the UKRI standard rate plus UK-level tuition fees; the University of St Andrews covers the Home-International fee difference.

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United Kingdom

University

University of St Andrews

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Keywords

Cell Biology
Molecular Biology
Neurology
Biology
Motor Control
Neuropsychology
Medical Science

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About this position

PhD opportunity at the University of St Andrews in the School of Psychology and Neuroscience on descending and ascending control of locomotor and respiratory central pattern generators (CPGs) in health and disease.

This project sits at the intersection of neuroscience, neurology, cell biology, and molecular biology, with a strong focus on motor control, respiratory control, and disease-relevant circuit mechanisms. The research will investigate how supraspinal descending pathways and ascending sensory/proprioceptive feedback regulate locomotor and respiratory CPGs, and how these pathways may be altered in disorders such as ALS.

Research themes and methods: viral tracing, tissue clearing, 3D imaging, in vivo Ca2+ imaging, optogenetics, chemogenetics, locomotor and respiratory behavioural analysis, markerless tracking, and machine-learning-based classification. The student will work with anatomical, functional, and behavioural datasets to map and test neural circuits controlling rhythmic movement and breathing.

Supervisors: Dr Ilary Allodi and Prof Gareth Miles, University of St Andrews.

Funding: 4-year competition-funded PhD via the EASTBIO BBSRC Doctoral Training Partnership. Open to UK and international students. Funding covers a stipend at the UKRI standard rate and UK-level tuition fees; the university covers the Home-International fee difference.

Eligibility/requirements: Applicants should be prepared for a multidisciplinary neuroscience project and provide the required application documents, including academic qualifications, English language qualification if applicable, and two references. UKRI eligibility guidance applies.

How to apply: Complete the EASTBIO Equality, Diversity and Inclusion survey and EASTBIO Application Form, then submit an online application via the University of St Andrews portal. Select the course PhD with internship and upload the required documents. Queries about the project should be directed to the supervisors; application queries can be sent to Rachel Horn at [email protected].

Funding details

This is a 4-year competition-funded PhD project through the EASTBIO BBSRC Doctoral Training Partnership. It is open to UK and international students and provides a stipend at the UKRI standard rate plus UK-level tuition fees; the University of St Andrews covers the Home-International fee difference.

What's required

Applicants should be interested in neuroscience, cell biology, molecular biology, neurology, and circuit-level approaches. The project highlights training in viral tracing, tissue clearing, in vivo calcium imaging, optogenetics, chemogenetics, advanced image analysis, and machine-learning-based behavioural quantification. English language qualification is required if applicable, and two references must be provided through the EASTBIO reference form.

How to apply

Download and complete the EASTBIO Equality, Diversity and Inclusion survey and the EASTBIO Application Form. Submit an online application through the University of St Andrews portal and select the course 'PhD with internship'. Include the completed EASTBIO form, academic qualifications, English language qualification if applicable, and two references on the EASTBIO reference form.

More information can be found here

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