PhD in Probing the Mechanism of Programmed Axon Death Using Protein Design University of Cambridge in United Kingdom

PhD opportunity: Transcellular Propagation of Tauopathies at the University of Cambridge, Department of Clinical Neurosciences. This project investigates how fibrillar tau aggregates spread between brain cells in neurodegenerative disease, with a focus on disease-specific tau folds and their selective accumulation in different CNS cell types. The research is especially relevant to neuroscience , neurology , biological sciences , and medical science . Research themes and methods: tau cytosolic en...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on neuroinflammatory mediators in the pathophysiology of traumatic brain injury (TBI) . The project investigates how maladaptive inflammation contributes to TBI and aims to identify mechanisms leading to brain swelling, raised intracranial pressure, and neuronal injury . The research integrates protein assays in biological fluids , neuro-intensive care monitoring , and patient outcomes , making it a strong...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on cerebral small vessel disease (cSVD) , with a focus on identifying shared mechanisms and therapeutic targets across genetic and sporadic disease forms. The project will use patient-derived induced pluripotent stem cell (iPSC) models to study vascular cell phenotypes in the neurovascular unit. The research combines cellular biology , molecular biology , functional assays , and transcriptomics/omics to un...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Mitochondrial Genetic Determinants of Multiple Sclerosis . This project investigates how mitochondrial genetic variants influence the outcome of multiple sclerosis (MS) . The research builds on prior genome-wide association studies (GWAS) that have identified more than 200 autosomal variants associated with MS, while extending the analysis to the mitochondrial genome. Using a dedicated mitochondrial var...

PhD opportunity in Inherited Eye Diseases and Mitochondrial Genetics at the University of Cambridge , Department of Clinical Neurosciences. This project sits at the intersection of neuroscience , medical science , and biology , with a strong translational focus on mitochondrial genetics , inherited eye diseases , and inherited optic neuropathies . The supervisor, Professor Patrick Yu-Wai-Man , leads research on progressive retinal ganglion cell loss, deep phenotyping, biomarker profiling, and ge...