Publisher
source

University of Basel

PhD position: Rationally engineered hydrogels to control osteogenesis via mechanoregulation (P2603) University of Basel in Switzerland

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

Available

Deadline

Oct 15, 2026

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Country

Switzerland

University

University of Basel

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Keywords

Biomedical Engineering
Materials Science
Biology
Stem Cell Biology
Thermoregulation
Mechanobiology
Osteogenesis
Viscoelasticity
Cell Culture Techniques
Computational Modelling
Hydrogel
Biomaterials
bio engineering

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About this position

PhD opportunity at the University of Basel in Switzerland, affiliated with the Swiss Nanoscience Institute, on rationally engineered hydrogels to control osteogenesis via mechanoregulation. The project is highly interdisciplinary and combines hydrogel synthesis, cell-instructive viscoelastic materials, cell characterisation, and computational modelling.

The research aims to understand how matrix properties influence osteogenesis in human dental pulp stem cells and how mechanical stimulation of the cellular microenvironment can be used to guide bone tissue engineering. The project’s objectives are to engineer hydrogels tuned to specific mechanical requirements for osteogenesis, study how targeted manipulation of the hydrogel affects mechanoregulation, and develop a computational model to predict cell response.

This PhD is suitable for candidates interested in biology, tissue engineering, materials science, chemistry, and computational modelling. Key technical areas include mammalian cell culture, microscopy, qRT-PCR, hydrogel formulation and characterisation, rheometry, atomic force microscopy, and data analysis using tools such as GraphPad, MATLAB, or R.

The position is fully funded and comes with a salary according to the Swiss National Science Foundation guidelines. The team offers close supervision, technical and administrative support, collaborative opportunities within the Medical Faculty and Faculty of Science, and access to core facilities including FACS, confocal microscopy, and electron microscopy.

Applicants should hold a master’s degree in a relevant field such as Nanosciences, Biomedical Engineering, Health Sciences and Technology, Biology, or Chemistry, from an institute accepted by the University of Basel. Strong English skills, good communication, and a self-driven, hands-on attitude are emphasized.

Applications are submitted online via the application link and information is also available at www.phd.nanoscience.ch. The deadline listed in the job details is 2026-10-15, while the description also notes the vacancy may be filled anytime and that the application should be completed before 31 December 2026.

Funding details

Available

What's required

Candidates should hold a Master in Nanosciences, Biomedical Engineering, Health Sciences and Technology, Biology, Chemistry, or a similar field from an institute of higher education accepted by the University of Basel. Experience in mammalian cell culture and analysis (microscopy, qRT-PCR), hydrogel formulation and characterisation (rheometry, atomic force microscopy), and data analysis/graphical representation (GraphPad, MATLAB, R or similar) is of special interest. Applicants should have fluency in English, good communication skills, and be highly self-driven with a hands-on work attitude.

How to apply

Apply through the online application platform at www.phd.nanoscience.ch. For questions, contact Dr. Andreas Baumgartner at [email protected] or the project leaders. Submit the completed application before the deadline; the vacancy may be filled earlier.

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