PhD Studentship in Biochemistry and Chemical Biology of the Genome and Epigenome University of Cambridge in United Kingdom

Funded PhD project at The Francis Crick Institute in London, United Kingdom, with Dr Frank Uhlmann and the Chromosome Segregation Laboratory. The project, Chromosome Organisation by Dynamic Cohesin Complexes , focuses on chromosome organisation , cohesin , chromatin loops , topologically associating domains , and the broader mechanisms of genome organisation and chromosome segregation . The lab studies how Structural Maintenance of Chromosome (SMC) complexes support sister chromatid cohesion, ch...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in structural biology, virology, biochemistry, biophysics, and molecular biology . This funded PhD project, supervised by Dr I Taylor , focuses on the ZAP antiviral response and how the proteins ZAP, KHNYN, and Trim25 assemble into molecular complexes that recognize viral RNA and trigger RNA degradation. The project aims to uncover the structure and mechanism of this antiviral system using protein purification, RNA-binding as...

Funded PhD project at the University of Bristol in the School of Biochemistry and Biomedical Sciences with Dr Maisem Laabei on targeted covalent macrocycles for immune-mediated diseases . The project focuses on the complement system and pathway-specific inhibition of key serine proteases, especially C1s and factor D , to develop more selective therapies for inflammatory and autoimmune conditions. Research themes include biochemistry , molecular biology , microbiology , phage display , chemical s...

We are hiring a Postdoctoral Researcher in Metalloenzyme Engineering at the Institute for Molecular Enzyme Technology , University of Düsseldorf, based at Forschungszentrum Jülich, Germany . The project focuses on nitrogenases , oxygen-sensitive metalloenzymes central to the global nitrogen cycle and sustainable fertilizer production. The successful candidate will conduct independent research on nitrogenases, develop AI-guided enzyme engineering approaches to improve nitrogenase stability, apply...

Funded PhD opportunity at the University of Kent in the Beal lab, working with David Beal and Michelle D. Garrett on Protein Hydras for cancer therapy. The project focuses on the development of therapeutically important antibodies and antibody drug conjugates (ADC) , especially bispecifics and polymodified ADC . This is a strong fit for students interested in chemical biology , chemical synthesis , molecular biology , biochemistry , and recombinant protein production . Funding: Tuition fees and ...