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The Wistar Institute

Post-Doctoral Fellow in Computational Biology, Single-Cell Genomics, and RNA Biology The Wistar Institute in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Competitive salary and an excellent benefits package are offered. The postdoctoral fellow will receive mentored training in single-cell and bulk multi-omics analysis, long-read sequencing technologies, microfluidics-free single-cell platform development, and cancer/RNA biology applications.

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Country

United States

University

The Wistar Institute

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Keywords

Cell Biology
Computer Science
Biomedical Engineering
Biology
Computational Biology
Rna Biology
Cancer
Software Development
Omics
Alternative Splicing
Long-read Sequencing
Genomic
Statistics
Bioinformatic
Transcriptomic

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About this position

Post-Doctoral Fellow (Computational Biology) – Srivastava Lab at The Wistar Institute in Philadelphia, United States.

The Srivastava Lab is a hybrid computational-experimental group working at the intersection of computational biology, single-cell genomics, RNA biology, cancer, bioinformatics, long-read sequencing, and multi-omics. The lab develops and applies cutting-edge single-cell long-read RNA sequencing technologies, including microfluidics-free platforms, and uses multi-omics approaches at single-cell resolution to study fundamental biological questions.

This postdoctoral role is specifically for a computational methods developer. The successful candidate will build algorithms and software for the lab’s single-cell long-read platform, including isoform-level quantification methods and multi-omics integration for disease-relevant single-cell data. The lab is looking for someone who can point to a tool, package, pipeline, or algorithm they have built and that others use. Strong Python and/or R programming in Linux/command-line environments is required, along with experience in single-cell and/or long-read sequencing data (Oxford Nanopore, PacBio). A first-author peer-reviewed publication is required.

Preferred experience includes molecular biology and sequencing library preparation, isoform-level transcriptomics, alternative splicing, transcript quantification, and reproducible software practices such as containers, version control, and workflow managers.

The position offers competitive salary and excellent benefits, plus mentored training in single-cell and bulk multi-omics analysis, long-read sequencing technologies, novel platform development, and cancer/RNA biology applications.

To apply, submit the online application via the job portal and email your CV, publication list (published and in preparation), cover letter, and three references to [email protected]. The posting links to Dr. Avi Srivastava’s publications and the Wistar Institute website for more information.

Funding details

Competitive salary and an excellent benefits package are offered. The postdoctoral fellow will receive mentored training in single-cell and bulk multi-omics analysis, long-read sequencing technologies, microfluidics-free single-cell platform development, and cancer/RNA biology applications.

What's required

Ph.D. or equivalent in computational biology, genomics, computer science, bioinformatics, or a related quantitative field. Applicants must demonstrate the ability to build and release computational methods such as a tool, package, pipeline, or algorithm used by others, with source code available. Strong programming and software-engineering skills in Python and/or R in a Linux/command-line environment are required, along with experience handling single-cell and/or long-read sequencing data (Oxford Nanopore, PacBio) and their computational workflows. At least one first-author peer-reviewed publication is required. Familiarity with molecular biology and sequencing library preparation, isoform-level transcriptomics, alternative splicing, transcript quantification, containers, version control, and workflow managers is preferred.

How to apply

Apply online through the job portal. Also email your CV with publication list, cover letter, and three references to Dr. Avi Srivastava at [email protected].

More information can be found here

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