Postdoc Research Associate in Progressive MS, iPSC/iNSC Models, Functional Genomics and Glial Biology University of Cambridge in United Kingdom

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on retrograde mitochondrial signalling, epigenetic reprogramming, glial toxicity, and neuroinflammation in progressive multiple sclerosis . The project focuses on how mitochondrial dysfunction and mitochondrial stress trigger nuclear signalling and epigenetic changes that may drive astrocytes toward a dysfunctional disease-associated radial glia-like (DARG) phenotype. The work is strongly research-oriented...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on Mitochondrial Genetic Determinants of Multiple Sclerosis . This project investigates how mitochondrial genetic variants influence the outcome of multiple sclerosis (MS) . The research builds on prior genome-wide association studies (GWAS) that have identified more than 200 autosomal variants associated with MS, while extending the analysis to the mitochondrial genome. Using a dedicated mitochondrial var...

Research Associate position at the University of Cambridge in a collaborative project across the labs of Professor Clémence Blouet and Professor Ragnhildur Thóra Káradóttir. The project sits at the interface of neuroscience and metabolic science , focusing on oligodendrocyte progenitor cells, remyelination, and brain repair in progressive multiple sclerosis. The work will test whether targeting incretin receptor agonists can promote remyelination and support repair in neurodegenerative disease. ...

PhD opportunity at the University of Cambridge / Cambridge Stem Cell Institute in neuroscience , stem cells , developmental biology , and cell biology . The project, “Neurotransmitter signalling to central nervous system progenitor cells,” is led by Professor Ragnhildur Thóra Káradóttir (Káradóttir Group). The research focuses on how oligodendrocyte precursor cells (OPCs) sense neuronal activity and neurotransmitter signals, decide whether to differentiate into myelin-producing oligodendrocytes ...

Two postdoctoral fellow positions are available in neurobiology at the MRC Laboratory of Molecular Biology with Dr Michel Goedert . The project focuses on the mechanisms underlying the assembly of alpha-synuclein into the amyloid filaments found in Lewy body diseases and multiple system atrophy in human brains. These are three-year positions funded by an ASAP (Aligning Science Across Parkinson's) grant. The collaboration includes researchers at MRC-LMB , University College London , University of...