PhD in Mitochondrial Genetic Determinants of Multiple Sclerosis University of Cambridge in United Kingdom

Georgetown University is advertising a Postdoctoral Associate position in the School of Medicine / Medical Center , within Dr. Jiang’s Cognitive Neuroimaging Laboratory . The lab uses neuroimaging to study cognitive function and cognitive impairments, with a strong focus on developing MRI methods for early detection and assessment of neural injury in neurodegenerative diseases such as Alzheimer’s disease and HIV-associated neurocognitive disorders . The successful candidate will help lead ongoin...

PhD opportunity at the University of Cambridge in Mathematical Modelling of Neurodegenerative Tauopathies – from systems to clinical impact. This project sits in the Department of Clinical Neurosciences and is supervised by Dr T Rittman . It builds on in silico mathematical models of neurodegenerative disorders associated with the tau protein and uses real-world cohort data from people with Progressive Supranuclear Palsy , Corticobasal Syndrome , and Frontotemporal Dementia . The research combin...

Postgraduate research project at the University of Southampton in the School of Electronics and Computer Science : Reliable forecasts of multiple sclerosis progression using conformal prediction . This is a PhD opportunity focused on developing machine learning methods for forecasting disability progression in multiple sclerosis with reliable, guaranteed uncertainty. The project uses conformal prediction and aims to create methods whose guarantees hold for clinically meaningful groups of patient...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on retrograde mitochondrial signalling, epigenetic reprogramming, glial toxicity, and neuroinflammation in progressive multiple sclerosis . The project focuses on how mitochondrial dysfunction and mitochondrial stress trigger nuclear signalling and epigenetic changes that may drive astrocytes toward a dysfunctional disease-associated radial glia-like (DARG) phenotype. The work is strongly research-oriented...

PhD opportunity at the University of Cambridge in the Department of Clinical Neurosciences on programmed axon death , SARM1 , NMNAT2 , and protein design . The project focuses on understanding the mechanism of programmed axon death, an intrinsic axonal death pathway implicated in neurodegenerative disease and injury. The work will use rational protein design to create variant forms of SARM1 or hybrid reporter constructs to study activation, stability, enzyme activity, and post-translational modi...