Duke University School of Medicine
1 week ago
Postdoctoral Associate in Biochemistry, Glycobiology, and Neurodegeneration Duke University School of Medicine in United States
Degree Level
Postdoc
Field of study
Cell Biology
Funding
Newly funded NINDS R01 project; the position is described as well-funded and provides access to state-of-the-art core facilities and a collaborative research environment. No stipend amount or specific salary is stated.
Country
United States
University
Duke University School of Medicine
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About this position
Postdoctoral Associate at Duke University School of Medicine
The Boyce Laboratory in the Department of Biochemistry at Duke University is recruiting a postdoctoral fellow for a newly funded NINDS R01 project. The project investigates how O-GlcNAc glycosylation regulates KLHL-family E3 ubiquitin ligases (including gigaxonin and KLHL3) and their substrates (neurofilaments and WNK kinases) in neuronal proteostasis, cytoskeletal dynamics, and ferroptotic cell death.
This is a highly interdisciplinary opportunity spanning biochemistry, chemical biology, cell signaling, glycobiology, live-cell imaging, cellular neurobiology, and organotypic brain slice models. The work is aimed at understanding mechanistic links between intracellular glycosylation and neurodegeneration. The exact project portfolio can be adjusted to fit the postdoc’s background, interests, and career goals.
Applicants should hold a Ph.D. or equivalent doctoral training in biochemistry, cell biology, neuroscience, or a related field. Experience in cellular neurobiology and/or O-GlcNAc signaling or glycobiology is strongly preferred, though not strictly required. The lab also welcomes strong candidates from adjacent areas who are eager to learn glycobiology approaches.
The position is on-site in Durham, North Carolina, United States. Duke describes the environment as rigorous, well-funded, inclusive, and highly collaborative, with access to state-of-the-art core facilities and opportunities to work across cell lines, primary neurons, and ex vivo brain tissue. The postdoc will be encouraged to develop an independent scientific identity, lead publications, present at national conferences, mentor junior researchers, and build the skills and preliminary data needed for an independent research career.
To apply, prepare a CV, a brief statement of research interests, and contact information for three references. Submit through Duke’s careers portal via the Apply now link.
Funding details
Newly funded NINDS R01 project; the position is described as well-funded and provides access to state-of-the-art core facilities and a collaborative research environment. No stipend amount or specific salary is stated.
What's required
Ph.D. or equivalent doctoral training in biochemistry, cell biology, neuroscience, or a related field is required. Strongly preferred experience includes cellular neurobiology and/or O-GlcNAc signaling or glycobiology more broadly. Candidates should be intellectually curious, work well independently and in teams, and be committed to rigorous, reproducible science; strong backgrounds in adjacent areas are also welcome if willing to learn glycobiology approaches.
How to apply
Prepare a CV, a brief statement of research interests, and contact information for three references. Submit the application through Duke's careers portal using the Apply now link.
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