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Postdoctoral Associate in Juvenile Dermatomyositis, Bioengineering, and Translational Science at Duke University Duke University in United States
Degree Level
Postdoc
Field of study
Biomedical Engineering
Funding
Available
Country
United States
University
Duke University
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About this position
Duke University is advertising a Postdoctoral Associate position in Durham, North Carolina, United States, focused on juvenile dermatomyositis (JDM), type I interferons, and bioengineered human muscle systems (myobundles). The project sits at the intersection of biomedical engineering, cell biology, immunology, physiology, and translational science, with a strong emphasis on understanding rare pediatric inflammatory muscle disease and improving patient care.
The postdoc will work in a collaborative, interdisciplinary research environment and will lead a translational project characterizing healthy and patient-derived muscle models, evaluating the effects of type I interferons on mitochondrial function and muscle physiology, and using advanced molecular and computational approaches to study disease mechanisms.
Core research activities include single-cell RNA sequencing (scRNA-seq) analysis, biostatistics and bioinformatics, cell culture in 2D and 3D systems, development and maintenance of engineered myobundles, contractile force measurements, mitochondrial stress testing, qPCR, Western blotting, histology, proteomics, and metabolomics. The role also involves experimental design, troubleshooting, documentation, data interpretation, and communication of findings through meetings, reports, presentations, and manuscripts.
Applicants must hold a PhD in a relevant discipline such as Cell Biology, Molecular Biology, Biomedical Engineering, Immunology, Physiology, or a related field. The posting highlights the need for expertise in biostatistics and bioinformatics, especially for scRNA-seq data, plus prior hands-on cell culture experience and the ability to conduct independent research. Strong analytical and scientific communication skills are expected.
Application materials requested are a current CV, a research statement, and contact information for 3-5 professional references. Apply through the Duke University careers portal using the provided link. No deadline is stated in the post.
Funding details
Available
What's required
PhD in a relevant scientific discipline such as Cell Biology, Molecular Biology, Biomedical Engineering, Immunology, Physiology, or a related field. Applicants should have expertise in biostatistics and bioinformatics, particularly single-cell RNA sequencing (scRNA-seq) analysis, previous hands-on cell culture experience, and experience designing and conducting independent scientific research. Strong analytical, problem-solving, and scientific communication skills are required, along with the ability to work independently and collaboratively in a multidisciplinary research environment and a commitment to scientific excellence, reproducibility, and innovation.
How to apply
Prepare a current CV, a research statement, and contact information for 3-5 professional references. Submit through Duke University Careers using the application link provided in the post.
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