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Postdoctoral Associate in Protein Self-Assembly at Interfaces and S-LATTICE Rice University in United States
Degree Level
Postdoc
Field of study
Biochemistry
Funding
Funded by a grant and soft/restricted funds; continued employment is contingent on renewal of funding. The postdoctoral associate is a full-time salaried exempt position.
Country
United States
University
Rice University
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About this position
Rice University is hiring a Postdoctoral Associate in BioSciences in Houston, Texas, United States. The position is in Dr. Caroline Ajo-Franklin’s lab and focuses on protein self-assembly at interfaces, especially the development of large, defect-free S-layer protein crystals for the S-LATTICE project.
The lab works at the intersection of biophysics, synthetic biology, materials science, biochemistry, and structural biology, engineering the interface between living microbes and non-living materials to create functional, sustainable materials. The successful candidate will develop and optimize protocols for assembling purified S-layer proteins at the air-water interface, express and purify proteins in E. coli, and build secretion-based production systems in multiple bacterial organisms.
The role includes coordinating with collaborators to assess crystal order, documenting and analyzing research data, presenting results at meetings, publishing findings, and helping with lab management and grant writing. The project is described as rapid and milestone-driven, and the job is part of an Advanced Research + Invention Agency-funded effort subject to contract negotiations.
Eligibility highlights: Ph.D. in Biophysics, Biochemistry, Structural Biology, Chemistry, Materials Science, or a closely related field. Strong experience with self-assembly, Langmuir troughs or protein interfaces, recombinant protein expression, and electron microscopy/ellipsometry is preferred. Additional experience with microbial chassis, surface-layer proteins, cryo-EM, AFM, and X-ray scattering is a plus.
Funding: This is a funded postdoctoral position supported by grant/soft/restricted funds; continued employment depends on funding renewal.
How to apply: Submit the application through Rice University’s careers portal and attach a resume in the Supporting Documents section, preferably as a PDF. No deadline is listed in the post.
Funding details
Funded by a grant and soft/restricted funds; continued employment is contingent on renewal of funding. The postdoctoral associate is a full-time salaried exempt position.
What's required
Ph.D. in Biophysics, Biochemistry, Structural Biology, Chemistry, Materials Science, or a closely related field. Required experience includes self-assembly using Langmuir troughs or the physical chemistry of proteins at liquid-air/liquid-solid interfaces, recombinant protein expression, secretion, and biochemical analysis, and knowledge of electron microscopy (TEM/STEM) and ellipsometry. Strong verbal and written communication, ability to publish and present research, collaborative skills, project/time management, data management, and adherence to lab safety are expected. Preferred qualifications include experience with E. coli, B. subtilis, and C. crescentus, surface-layer proteins or lattice-forming proteins, lipid films and protein-lipid interactions, cryo-EM, AFM, GI-WAXS, SAXS, mentoring, and equipment management.
How to apply
Apply through the Rice University careers portal. Attach a resume in the Supporting Documents section, preferably as a PDF. For questions, contact [email protected].
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