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The Francis Crick Institute

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Postdoctoral Fellow in Scientific Machine Learning and Mechanistic Modelling (Fröhlich Lab) Francis Crick Institute in United Kingdom

Degree Level

Postdoc

Field of study

Computer Science

Funding

Full-time fixed-term 4-year postdoctoral position. Salary starts from £47,500 with benefits, subject to skills and experience. UK work sponsorship is available for eligible applicants.

Deadline

Sep 24, 2026

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Country

United Kingdom

University

The Francis Crick Institute

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Keywords

Computer Science
Biomedical Engineering
Biology
Mathematics
Computational Biology
Cell Signaling
Mathematical Biology
Statistics
Differential Equation
Physics
ML

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About this position

Postdoctoral Fellow opportunity in the Fröhlich Lab at the Francis Crick Institute, London, focused on scientific machine learning, computational biology, mechanistic modelling, and single-cell data.

The project aims to develop the next generation of deep mechanistic models for biological systems, extending models from population-level to single-cell data by combining neural networks with mechanistic differential equation models. The successful candidate will work with cutting-edge datasets generated in the lab and from public resources, and will help develop open-source computational tools.

Research interests mentioned include live-cell imaging, flow matching, optimal transport, and cell-cycle modelling. The role is highly interdisciplinary, bringing together mathematics, physics, biology, engineering, and data science.

Eligibility: PhD in mathematics, physics, data science, engineering, systems biology, or a related field, or near completion of the PhD. Strong Python programming, knowledge of mathematical models of biological systems, numerical methods for differential equations, independent research experience, and strong scientific communication are required. Experience with JAX/PyTorch, single-cell methods, cell biology, biochemistry, software development, or high-performance computing is desirable.

Funding and terms: Full-time, fixed-term 4-year postdoctoral post. Salary from £47,500 plus benefits. UK visa sponsorship is available for eligible applicants.

Location: Francis Crick Institute, London, United Kingdom.

Application: Apply via the Nature Careers external application page. Closing date: 24 Sep 2026.

Funding details

Full-time fixed-term 4-year postdoctoral position. Salary starts from £47,500 with benefits, subject to skills and experience. UK work sponsorship is available for eligible applicants.

What's required

PhD in mathematics, physics, data science, engineering, systems biology or a related field, or be in the final stages of PhD submission. Strong scientific programming skills in Python are essential, along with knowledge of mathematical models of biological systems and numerical methods for differential equations. Applicants should have experience developing and pursuing independent research ideas, strong written and verbal scientific communication skills, a collaborative cross-disciplinary approach, interest in applying computational methods to biological questions, and commitment to reproducible research and open science. Desirable experience includes JAX or PyTorch, single-cell methods such as optimal transport or flow matching, cell biology/biochemistry relevant to signalling and cell-cycle pathways, modern software development practices, or high-performance computing.

How to apply

Apply on the Nature Careers website via the external application link. Review the full job description and ensure you meet the essential criteria before submitting your application. If you need assistance applying, contact [email protected].

More information can be found here

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