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King's College London

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Postdoctoral Research Associate in Actin Cytoskeleton and Cryo-EM at King's College London King's College London in United Kingdom

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Full-time fixed-term post for one year. Salary details are referenced in the post for candidates awaiting PhD award (Grade 5, spine point 30) and after PhD confirmation (Grade 6), but no stipend or tuition funding is mentioned.

Deadline

Sep 13, 2026

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Country

United Kingdom

University

King's College London

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Keywords

Cell Biology
Biochemistry
Molecular Biology
Biomedical Engineering
Materials Science
Biophysics
Biology
Structural Biology
Cryo-electron Microscopy
Neuropsychology
Medical Science
Cancer

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About this position

King's College London is advertising an internal-only Postdoctoral Research Associate in the Atherton lab at the Randall Centre for Cell & Molecular Biophysics, within the School of Basic & Biomedical Sciences and the Faculty of Life Sciences & Medicine.

The project focuses on actin-binding proteins and how they remodel the eukaryotic cytoskeleton, with relevance to neuronal development, synaptic plasticity, cell-cell interactions, viral infection, and cancer invasion. The role is strongly centered on structural biology, especially single-particle cryo-EM and in situ cryo-electron tomography, supported by cell biology, molecular biophysics, biochemistry, and molecular biology.

The lab has access to major cryo-EM infrastructure, including an on-site autoloading JEOL cryoARM200 + K3 detector and a Titan Krios with FIBSEM equipment at nearby London sites. The post is full-time, fixed term for one year, and is laboratory-based with most work on site.

Applicants should have a PhD awarded or near completion in a relevant area and strong experience in protein expression/purification, structural biology, and cell culture. Essential skills include cryo-EM, Linux command line use, and cryo-EM processing software. Desirable experience includes cryo-ET sample preparation and image processing, fluorescence microscopy/CLEM, neuron and glial cell preparation for in situ cryo-ET, and use of Relion, Cryosparc, and related pipelines.

This vacancy is explicitly open to internal candidates only. Applications should include a CV and supporting statement addressing the essential criteria, with evidence for desirable criteria where possible. The advert notes that the university may close the vacancy early if there is a strong field of applicants.

Funding details

Full-time fixed-term post for one year. Salary details are referenced in the post for candidates awaiting PhD award (Grade 5, spine point 30) and after PhD confirmation (Grade 6), but no stipend or tuition funding is mentioned.

What's required

PhD awarded or near completion in a relevant research area. Essential experience includes cryo-electron microscopy/structural biology of filaments, sample preparation and data collection, actin cytoskeleton and associated proteins, Linux command line usage, cryo-EM processing software, prokaryotic (E. coli) cell culture with protein expression and purification, eukaryotic cell culture and protein expression, and basic molecular biology and biochemistry techniques. Desirable experience includes cellular cryo-electron tomography, light/fluorescence microscopy or CLEM, preparing neurons and glial cells for in situ cryo-ET, filament processing in Relion/Cryosparc/cryo-ET software, and HPC cluster use.

How to apply

Apply via the King's College London jobs portal using the View or Apply link. Submit a CV and a supporting statement showing how you meet the essential criteria, and include evidence for desirable criteria where possible. Apply early because the advert may close before the deadline if enough applications are received.

More information can be found here

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