University of Oxford
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1 week ago
Postdoctoral Research Scientist in Parkinson’s Disease, CRISPR Functional Genomics and Neuronal Mitochondrial Biology University of Oxford in United Kingdom
Degree Level
Postdoc
Field of study
Biomedical Engineering
Funding
Fixed-term, full-time post for 32 months. The post advertises standard University of Oxford employment benefits including pension, annual leave, childcare services, family leave, and travel loans; no stipend or tuition funding is mentioned.
Deadline
Oct 19, 2026
Country
United Kingdom
University
University of Oxford

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About this position
University of Oxford is advertising a Postdoctoral Research Assistant / Postdoctoral Research Scientist position in the Department of Physiology, Anatomy & Genetics and the Kavli Institute for Nanoscience Discovery in Oxford, England, United Kingdom.
The project focuses on Parkinson’s disease, mitochondrial function, and cellular metabolism in human neurons. The successful candidate will work in the Ryan Group within the Laboratory of Molecular Neurodegeneration under the supervision of Dr Brent Ryan. The research uses CRISPRi/a functional genomics, sgRNA library design and cloning, iPSC-derived cortical neurons and dopaminergic neurons, high-content imaging, quantitative cellular phenotyping, and assays of neuronal metabolism.
This is a strong opportunity for candidates interested in neuroscience, cell biology, functional genomics, mitochondrial biology, and neurodegenerative disease. The group highlights expertise in CRISPRi/a, iPSC culture, neuronal differentiation, mitochondrial phenotyping, and quantitative data analysis, and will provide training and support for methods outside the applicant’s current expertise.
Eligibility highlights: a PhD/DPhil in neuroscience or cell/molecular biology (or equivalent), experience with neuronal/glial culture preferably in human pluripotent stem cells, experience setting up cellular/image-based assays, and knowledge of neurodegenerative disorders. Desirable experience includes lysosomal and mitochondrial biology, CRISPR methods, Cell Painting, metabolic flux assays, publication experience, and microscopy image analysis pipelines.
Employment details: fixed-term, full-time for 32 months. The post includes standard Oxford staff benefits such as pension, annual leave, childcare services, family leave, and travel loans. No scholarship or student stipend is mentioned.
Application deadline: 19 October 2026, 12 noon. Interviews are expected during the week commencing 26 October 2026 and may be held in person or via Microsoft Teams.
How to apply: submit an online application with a supporting statement, CV, and details of two referees via the Oxford recruitment portal. Informal enquiries may be directed to the DPAG HR Team at [email protected].
Funding details
Fixed-term, full-time post for 32 months. The post advertises standard University of Oxford employment benefits including pension, annual leave, childcare services, family leave, and travel loans; no stipend or tuition funding is mentioned.
What's required
A PhD/DPhil in neuroscience or cell/molecular biology, or equivalent, is required. Candidates should have experience in neuronal or glial cell culture, preferably human pluripotent stem cells, and in setting up cellular assays such as image-based experiments. Knowledge of neurodegenerative disorders is essential. Desirable experience includes lysosomal and mitochondrial biology, CRISPR methodologies, Cell Painting, metabolic flux assays, publication track record, and microscopy image analysis pipelines. Applicants should be highly motivated, creative, collaborative, and able to work across teams.
How to apply
Submit an online application with a supporting statement addressing the selection criteria, your CV, and details of two referees. Apply through the University of Oxford recruitment portal before the deadline.
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