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Rosalind Franklin Institute

Postdoctoral Research Associate in Structural Cell Biology and Cryo-Electron Tomography The Rosalind Franklin Institute in United Kingdom

Degree Level

Postdoc

Field of study

Computer Science

Funding

Full-time 3-year fixed-term postdoctoral research associate position with salary £39,500 per annum depending on skills and experience; candidates who have submitted their PhD/DPhil thesis may start at £38,500 until qualification completion.

Deadline

Nov 8, 2026

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Country

United Kingdom

University

Rosalind Franklin Institute

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Keywords

Computer Science
Biomedical Engineering
Materials Science
Biology
Aging
Cryo-electron Microscopy
Neuropsychology
Mitochondrial Biology
Medical Science
Cytoskeleton Dynamics
Neurodegenerative Disease

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About this position

Research Associate in Structural Cell Biology at The Rosalind Franklin Institute (Harwell, United Kingdom).

This is a postdoctoral opening focused on structural cell biology, cryo-electron tomography, in-situ structural biology, and computational reconstruction of macromolecular structures from human tissue data. The Grange group is developing tools to image the 3-dimensional organisation of macromolecular complexes within brain tissues, using fast vitrification of surgical biopsies, cryo-focused ion beam milling, cryo lift-out, and electron tomography.

The project will investigate cytoskeletal and mitochondrial changes during aging and neurodegeneration, with a strong emphasis on developing and streamlining computational workflows for structure determination from tissue sources. The successful candidate will work with partners at Imperial College London, University College London, and the University of Oxford to coordinate specimen procurement, acquire high-quality cryo-electron tomography data, and build pipelines for analysing macromolecular organisation and diversity.

Applicants should hold a PhD/DPhil (or equivalent), or have submitted their thesis. The role is full-time and fixed-term for 3 years. Salary is £39,500 per annum depending on skills and experience, with a starting salary of £38,500 for candidates awaiting thesis completion.

How to apply: upload a CV and cover letter via the application link on the job page. The closing date is 8 November 2026 at 23:59.

Funding details

Full-time 3-year fixed-term postdoctoral research associate position with salary £39,500 per annum depending on skills and experience; candidates who have submitted their PhD/DPhil thesis may start at £38,500 until qualification completion.

What's required

Applicants must hold a PhD/DPhil (or equivalent), or have submitted their thesis with appointment initially at a lower salary until completion. The role seeks a motivated postdoctoral researcher with scientific knowledge in structural cell biology, in-situ structural biology, cryo-electron tomography, computational reconstruction, and related experimental/data analysis skills. Experience working with human tissue, macromolecular complexes, and collaborative research with clinicians and multidisciplinary teams is relevant.

How to apply

Upload a CV and cover letter through the application link on the job page. Review the Job Information Pack before applying. Applications close at 23:59 on Sunday 8 November 2026.

More information can be found here

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