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University of Oxford

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Postdoctoral Researcher in Epigenetic Control of Gene Expression in Leukaemia and Haematopoiesis University of Oxford in United Kingdom

Degree Level

Postdoc

Field of study

Biology

Funding

Fixed-term postdoctoral position until 31 March 2027, funded by the Medical Research Council.

Deadline

Sep 11, 2026

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Country

United Kingdom

University

University of Oxford

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Keywords

Biology
Gene Expression
Medical Science
Chromatin Biology
Hematopoiesis
Transcription
Epigenetic
Genomic

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About this position

University of Oxford is advertising a Postdoctoral Researcher position in epigenetic control of gene expression in leukaemia and haematopoiesis, based in Oxford, England, United Kingdom. The project sits in the Professor Thomas Milne group and focuses on how chromatin proteins, nucleosomes, transcriptional regulators, chromatin structure, regulatory interactions, transcription, and three-dimensional genome organisation shape gene expression in blood development and leukaemia.

The research will combine genome engineering, acute protein perturbation, and advanced genomic/epigenomic approaches. The successful candidate will plan and carry out independent research, generate and analyse high-quality genomic data, optimise experimental methods, prepare results for publication, and contribute to supervision and scientific development within the group.

Applicants should hold a PhD or be close to completion at the time of application in molecular biology, genetics, epigenetics, chromatin biology, or a related discipline. Required experience includes chromatin biology, transcription/gene regulation, mammalian cell culture, CRISPR/Cas9 genome editing, and genomic or epigenomic analysis. Strong understanding of transcriptional and chromatin regulatory mechanisms is essential. Desirable experience includes mouse embryonic stem cells, inducible protein degradation systems, Micro Capture-C, CUT&Tag, ChIP-seq, ATAC-seq, and TT-seq.

The post is a fixed-term contract until 31 March 2027 and is funded by the Medical Research Council. Applications must be submitted online with a CV and supporting statement. The deadline is 11 September 2026 at 12:00 noon, and interviews are scheduled for 18 September 2026.

Funding details

Fixed-term postdoctoral position until 31 March 2027, funded by the Medical Research Council.

What's required

PhD, or near completion with thesis submitted at the time of application, in molecular biology, genetics, epigenetics, chromatin biology or a related discipline. Research experience in chromatin biology, transcription or gene regulation is required, along with experience in mammalian cell culture, CRISPR/Cas9 genome editing, and genomic or epigenomic approaches. Experience analysing genomic datasets and a strong understanding of transcriptional and chromatin regulatory mechanisms are essential. Desirable experience includes mouse embryonic stem cells, inducible protein degradation systems, Micro Capture-C, CUT&Tag, ChIP-seq, ATAC-seq or TT-seq.

How to apply

Apply online through the University of Oxford recruitment portal. Upload a CV and supporting statement with the application. Submit before 12:00 noon on Friday 11 September 2026.

More information can be found here

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