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International PhD Programme (IPP) Mainz, Institute of Molecular Biology

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PhD Position: Condensates in Transcription Regulation (m/f/d) International PhD Programme (IPP) Mainz in Germany

Degree Level

PhD

Field of study

Biology

Funding

Available

Deadline

Oct 15, 2026

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Country

Germany

University

International PhD Programme (IPP) Mainz, Institute of Molecular Biology

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Keywords

Biology
Gene Expression
Microscopy
Transcriptional Regulation
Super-resolution Microscopy
Chromatin Biology
Epigenetic
Genomic

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About this position

The International PhD Programme (IPP) Mainz at the Institute of Molecular Biology is offering a fully funded PhD position in Condensates in Transcription Regulation under the supervision of Sandra Schick. This project sits within a vibrant, international PhD environment in Mainz and is part of a broad life-sciences programme covering topics such as epigenetics, DNA repair, ageing, and neural memory.

The project investigates how transcriptional condensates contribute to the early stages of gene regulation, with a particular focus on how chromatin and transcriptional regulators cooperate to prime chromatin for transcription initiation. The research will dissect the roles of co-activators, transcription factors, chromatin, chromatin modifiers, and RNA polymerase II in condensation, condensate properties, and function. A key goal is to understand how different condensate types emerge, influence each other, and transition through distinct transcriptional stages.

Methodologically, the project combines established reporter lines with advanced microscopy, including live-cell confocal microscopy and super-resolution microscopy. The work also includes CRISPR-based approaches, genomics, and proteomics. Cellular experiments will be complemented by in vitro studies in the Wittmann lab at IMB and modelling work in the Speck lab at the University of Stuttgart. The project is embedded in the collaborative research consortium SFB1551, which is noted as pending a funding decision in November 2026.

Applicants should hold a Master’s degree or equivalent, have a good command of English, and be able to provide two letters of reference. The IPP describes itself as an interdisciplinary and lively international environment with English as the working language, advanced training in scientific and professional skills, and access to state-of-the-art core facilities. The position is advertised as a fully funded PhD with support until thesis completion.

The application deadline is 15 October 2026. Interviews are scheduled for 18-19 January 2027 at IMB in Mainz, and the anticipated starting window is 1 February to 31 July 2027. Applicants are instructed to apply via the online form and select Schick (Cond) as the group preference.

Funding details

Available

What's required

Master's degree or equivalent in a relevant field, good command of English, an interactive personality, and two letters of reference are required.

How to apply

Apply through the online form via the IPP Mainz application page. Select "Schick (Cond)" as your group preference in the application platform. Submit your application by 15 October 2026; interviews are planned for 18-19 January 2027 in Mainz.

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