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Karolinska Institutet

Postdoctoral Researcher in Structural Virology and Cryo-EM Karolinska Institutet in Sweden

Degree Level

Postdoc

Field of study

Biochemistry

Funding

Temporary full-time postdoctoral employment at Karolinska Institutet; salary is monthly salary, but no stipend or funding amount is specified.

Deadline

Oct 20, 2026

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Country

Sweden

University

Karolinska Institutet

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Keywords

Biochemistry
Molecular Biology
Chemistry
Biomedical Engineering
Biophysics
Biology
Cryo-electron Microscopy
Medical Science
Rna Viruses
Physics

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About this position

Karolinska Institutet is advertising a Postdoctoral Researcher in Structural Virology position in the research team led by Leo Hanke at the Department of Medicine, Solna, in Sweden.

The project focuses on RNA virus biology, virus entry, replication, and immune recognition using structural biology approaches. The main methods include cryo-EM, biochemical and biophysical studies, image processing, three-dimensional reconstruction, atomic model building, and structural interpretation. The group also uses nanobodies as structural probes to study viral neutralization and transient conformational states.

The successful candidate should have a PhD in structural biology, biochemistry, biophysics, molecular biology, or a related field, plus documented cryo-EM experience and a strong publication record. Required practical skills include recombinant protein expression and purification, cryo-EM sample preparation, grid optimization, data collection, and software such as RELION, cryoSPARC, Coot, Phenix, and ChimeraX. Experience with membrane proteins, viral glycoproteins, antibodies/nanobodies, X-ray crystallography, computational structural biology, AlphaFold modelling, or advanced biophysics is considered an advantage.

This is a temporary full-time postdoctoral position. The application must include a PhD certificate, CV with thesis and academic details, publication list, and a one-page summary of current work. Applications are submitted through the Varbi recruitment system.

Deadline: 20 October 2026.

Funding details

Temporary full-time postdoctoral employment at Karolinska Institutet; salary is monthly salary, but no stipend or funding amount is specified.

What's required

PhD in structural biology, biochemistry, biophysics, molecular biology, or a related field; documented experience in cryo-EM; proven track record of applying structural approaches to biological questions; hands-on experience in recombinant protein expression and purification; substantial practical expertise in cryo-EM sample preparation, grid optimization, and data collection; experience with RELION, cryoSPARC, Coot, Phenix, and ChimeraX; advantageous experience with membrane proteins, viral glycoproteins, protein complexes, antibodies/nanobodies, X-ray crystallography, computational structural biology, AlphaFold-based modelling, or advanced biophysical characterization; strong publication record; ability to work independently and collaboratively; excellent written and spoken English.

How to apply

Prepare the required documents in English or Swedish: PhD certificate, complete CV with thesis and academic details, publication list, and a one-page summary of current work. Submit the application through the Varbi recruitment system before the deadline.

More information can be found here

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