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University of Oxford

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Postdoctoral Scientist in Molecular Biology of Neoantigen pMHC-TCR Interactions in Sarcoma University of Oxford in United Kingdom

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Full funding available

Deadline

Sep 4, 2026

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Country

United Kingdom

University

University of Oxford

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Keywords

Cell Biology
Molecular Biology
Biology
Medical Science
Sarcoma Biology

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About this position

Postdoctoral Scientist opportunity at the Sir William Dunn School of Pathology, University of Oxford in molecular biology, cell biology, and cancer immunology. The project focuses on neoantigen prediction, TCR selection, and pMHC-TCR molecular and cellular interactions, with emphasis on neoantigens associated with chromosomal translocations in rare cancers, especially sarcoma.

The post is part of collaborative grants aimed at building the basic science and experimental foundation for translation of pMHC-TCR interactions into personalised TCR therapies. The successful candidate will work independently within a multidisciplinary research group and contribute to experimental design, technique development, data generation, and publication.

Key methods and interests include mammalian and bacterial protein expression, surface plasmon resonance, T-cell reporter assays, and related molecular/cellular protocols. Applicants should have a PhD/DPhil (or be very close to completion) in a directly relevant area and should be able to manage their own research, present at scientific meetings, write for peer-reviewed journals, and contribute to high-quality research supervision.

This is a fixed-term post for up to 24 months, starting 1 October 2026. Salary is Research Grade 7.2 at £40,514 per annum. Applications close on 4 September 2026 at 12:00, and interviews are expected in mid-September online. Apply via the Oxford recruitment portal and upload a CV plus supporting statement.

Funding details

Full funding including tuition fees and living expenses is available for this position. The scholarship covers all educational costs and provides a monthly stipend.

How to apply

Please submit your application including a cover letter, CV, academic transcripts, and contact information for two references. Applications should be sent via the online portal before the deadline.

More information can be found here

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