Postdoctoral Researcher in Cell-State Plasticity in Gliomas (IDH-mutant glioma, tumor genomics, epigenetics)
The Department of Neuro-Oncology at the
University Hospital Bonn
is recruiting a
Postdoctoral Researcher in Cell-State Plasticity in Gliomas
(m/w/d). This is a full-time research position (38.5 hours/week) in the newly established Experimental Neuro-Oncology group led by
Prof. Sevin Turcan
.
The project sits at the interface of
tumor genomics
,
epigenetics
,
chromatin biology
,
functional perturbation
, and
cell-state plasticity
, with a strong focus on
IDH-mutant glioma
. The lab aims to understand how oncometabolite-driven epigenetic reprogramming creates persistent tumor cell states and how these states evolve during malignant progression and recurrence.
The successful candidate will lead an independent project using patient-derived glioma models, tumor genomics, DNA methylation, RNA-seq, ATAC-seq, CUT&Tag/CUT&RUN, selected single-cell/spatial technologies, and functional validation approaches. The role also involves close collaboration with computational partners and contributes to a broader research program on glioma evolution, epigenetic memory, and therapeutic state rewriting.
Eligibility highlights:
a doctoral degree in biology, cancer biology, neuroscience, genomics, or a related field (or near completion); strong interest in brain tumor biology, tumor evolution, and epigenetic regulation; hands-on molecular/cellular biology experience; and very good English. Experience with cancer models, stem-cell/organoid systems, patient-derived cultures, CRISPR, bioinformatics, or single-cell/nuclei assays is an advantage. German is helpful but not required.
Funding and conditions:
the position is initially limited to two years, with the possibility of extension. Compensation follows TV-L / TV-Ä at university hospitals and includes standard benefits and additional payments.
How to apply:
send a single PDF containing a cover letter, CV with publication list, and contact details for two to three referees. Quote vacancy reference
ST-47008
and email the application to
[email protected]
. The deadline is
2026-09-15
.
