Karolinska Institutet
6 days ago
Doctoral position in translational research on leukemia niche Karolinska Institutet in Sweden
Degree Level
PhD
Field of study
Molecular Biology
Funding
Available
Deadline
Sep 25, 2026
Country
Sweden
University
Karolinska Institutet
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About this position
Karolinska Institutet is offering a doctoral position in translational research on the leukemia niche, based in the Hong Qian group at the Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge. The project focuses on acute myeloid leukemia (AML) and aims to understand how the leukemic microenvironment contributes to disease progression, drug response, and tissue infiltration. The long-term goal is to identify niche-based therapeutic targets that can improve outcomes for patients with AML.
The doctoral student will work with patient samples and mouse models and gain hands-on experience with multi-color flow cytometry, confocal imaging, lineage tracing, in vitro and in vivo stem cell assays, co-culture and transplantation experiments, RNA sequencing, droplet digital PCR, and CRISPR/Cas9-based gene editing. The project will evaluate the functional effects of newly identified niche factors and explore their correlation with AML infiltration outside the bone marrow and responses to therapy.
Supervision will be provided primarily by Dr. Hong Qian, with co-supervision by Dr. Martin Jädersten and Dr. Petter Woll. The position is designed for a motivated doctoral student who wants to develop both theoretical understanding and practical research skills in a highly collaborative translational environment.
Karolinska Institutet is one of the world’s leading medical universities and offers a creative research environment, access to a wide range of doctoral courses, international collaboration opportunities, and a formal doctoral studentship with salary. The university also provides employee benefits such as access to a gym and reimbursements for medical care.
Eligibility requires a Master’s degree in Medicine, Biomedicine, or translational medical research, or equivalent prior academic preparation. Applicants must also demonstrate English proficiency equivalent to English B/English 6 in Sweden. Experience with mice, flow cytometry, cell culture, and co-culture with mesenchymal stem cells is particularly valued, and a medical background is preferred. The selection process emphasizes relevance of academic background, analytical skill, and other experiences relevant to doctoral studies in the subject.
The application deadline is 2026-09-25. Applications must be submitted through the Varbi recruitment system and should include a personal letter, CV, degree projects and publications if available, and documentation proving eligibility and relevant skills.
Funding details
Available
What's required
Applicants must have a Master’s degree in Medicine, Biomedicine, or translational medical research, or meet the equivalent general eligibility requirement of at least 240 credits with at least 60 advanced-level credits. English proficiency equivalent to Swedish upper secondary school English B/English 6 is required. Desired qualifications include good spoken and written English, strong organizational skills, ability to work flexibly in a high-paced research environment, experience with mice, flow cytometry, and cell culture, especially co-culture with mesenchymal stem cells. A medical training background is preferred, and personal suitability will be an important selection criterion.
How to apply
Apply through the Varbi recruitment system using the application link. Submit a personal letter, CV, degree projects and publications if any, supporting documents showing relevant skills, and documents proving general and specific eligibility. Applications may be written in English or Swedish.
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