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US Food and Drug Administration

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FDA Fellowship in Immunogenicity of Therapeutic Proteins U.S. Food and Drug Administration (FDA) in United States

Degree Level

Postdoc

Field of study

Cell Biology

Funding

Monthly stipend commensurate with educational level and experience; initial one-year appointment, renewable upon recommendation and contingent on available funds.

Deadline

Dec 18, 2026

Country flag

Country

United States

University

US Food and Drug Administration

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Keywords

Cell Biology
Immunology
Biochemistry
Computer Science
Molecular Biology
Chemistry
Biomedical Engineering
Biology
Mathematics
Computational Biology
Medical Science
Genome Editing
Immunity
Econometric
Statistics
Bioinformatic

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About this position

This research fellowship is based in the Division of Hemostasis, Center for Biologics Evaluation and Research (CBER), at the U.S. Food and Drug Administration in Silver Spring, Maryland. The project sits within a research program focused on unwanted immune responses to therapeutic proteins, with a particular emphasis on protein products and Cas proteins used in gene editing.

Working in the laboratory of Zuben E. Sauna, the fellow will help develop tools to understand the safety consequences of immune responses to diverse Cas proteins and to neo-epitopes generated by off-target gene editing. The research uses a combination of in silico, in vitro, and ex vivo approaches, drawing on cell and molecular biology, computational biology, biochemistry, and immunology.

The lab’s recent publications show a strong focus on pre-existing immunity to CRISPR-associated nucleases, antigen presentation, T-cell and B-cell responses, and risk assessment for novel modalities. The position offers training in cutting-edge technologies directly relevant to public health, as well as opportunities to participate in seminars, formal training, and collaborative projects with academia and industry.

The appointment is a full-time research fellowship in a highly translational regulatory-science environment at FDA CBER.

Funding details

Monthly stipend commensurate with educational level and experience; initial one-year appointment, renewable upon recommendation and contingent on available funds.

What's required

Applicants should have received a master's or doctoral degree in a relevant field such as Immunology, Biochemistry, Biology, Pharmaceutical Sciences, Bioinformatics, or Computational Biology, or be currently pursuing one of these degrees with completion before the appointment start date. The degree must have been received within the last five years of the appointment start date. Preferred experience includes advanced techniques in immunology, biochemistry, molecular biology, and cell biology, or experience in bioinformatics, applied statistics, and computational biology. Applicants should be willing to learn new technologies and methods and work outside their comfort zone. U.S. citizens, lawful permanent residents, and certain foreign nationals are eligible; non-U.S. citizens must meet the program’s immigration-status requirements and background-investigation constraints.

How to apply

Apply through the Zintellect opportunity page by scrolling to the bottom and clicking APPLY. Submit an application, transcripts, a current resume/CV, and one educational or professional recommendation. If you have questions, email [email protected] and include the reference code FDA-CBER-2026-0091.

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